Pre-cancer atlases of cutaneous and hematologic origin (PATCH Center)

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ABSTRACT The overall aims of the Center for Pre-cancer Atlases of Cutaneous and Hematologic Origin (PATCH Center) will pivot in the supplemental year to focus on data analysis and dissemination. The Administration and Project Management team will focus on the scientific management of the Center, communicate with NCI staff and HTAN Centers, and ensure regular data deposition. They will guide the other Center members to focus on all activities related to the completion and dissemination of the Center atlas. We anticipate the biospecimen and clinical teams will focus on curating clinical and biospecimen metadata and participating in the interpretation of results for publication and other dissemination activities. Most characterization activities for the atlas and the SARDANA TNP will be completed prior to the initiation of the supplement, but additional characterization will be performed for quality assurance and follow up experimentation during the publication process. The bulk of the activities will be in data analysis, software development, and dissemination of complex image data. The Center will be working on 3D segmentation and visualization tools, improvements to the MCMICRO pipeline, and advancements to Minerva Story tools to accommodate 3D visualization as well as clinical and biospecimen metadata. Our Center will continue to work with the DCC to develop and optimize the process for sharing highly complex imaging data.