Administrative Core

行政核心

• 批准号: 10685411
• 负责人: Suresh S Ramalingam
• 金额: $ 25.36万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-07-10 至 2024-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10685411
• 关键词: Accounting; Advocate; Basic Science; Budgets; Cancer Patient; Clinical Ethics; Clinical Research; Clinical Trials; Collaborations; Committee Members; Companions; Dedications; Development; Educational workshop; Ensure; Ethics; Evaluation; Funding; Goals; Grant; Human Resources; Institution; Malignant neoplasm of lung; Mission; Monitor; Patients; Performance; Pilot Projects; Play; Problem Solving; Progress Reports; Regulation; Reporting; Research; Research Personnel; Research Project Grants; Resources; Role; Translating; Translational Research; Travel; Universities; career; clinical application; data management; data sharing; design; meetings; member; operation; organizational structure; patient engagement; programs; remediation; translational potential

SUMMARY/ABSTRACT The Administrative Core will execute the administrative, coordination, data sharing, and evaluation functions of the Emory Lung Cancer SPORE to ensure that the research projects, cores and pilot projects of the Career Enhancement Program (CEP) and Developmental Research Program (DRP) perform at their best levels. The Administrative Core will play a pivotal role in monitoring progress, overseeing the change in direction of any under-performing projects, and replacing them with new translational projects as needed. To achieve its goals, the Core will perform the following administrative functions: (1) Provide necessary resources and fiscal oversight/accounting; (2) Acquire and allocate institutional matching funds to facilitate clinical trials and pilot projects; (3) Administer the CEP and DRP programs; (4) Prepare yearly non-competing progress reports; (5) Ensure the ethical design and conduct of the proposed clinical trials in Projects 1 and 2 and the ethics companion study associated with Project 1. The Core will also undertake the following coordination functions: (1) Arrange and coordinate monthly SPORE investigators meetings, and the annual retreat; (2) Arrange travel to SPORE-related investigator workshops & NCI Translational Science meeting; (3) Plan and facilitate annual meetings of the Internal and External Advisory Boards; (4) Plan and facilitate monthly Executive Committee Meetings; (5) Provide and coordinate SPORE-SPORE and SPORE-NCI interfaces; (6) Coordinate to assure the compliance of all research projects with NCI, FDA and other federal, local and institutional regulations; (7) Engage patient advocates to integrate a patient perspective. Lastly, the Core will perform the following planning and evaluation functions: (1) Regular monitoring and assessment of research progress; (2) Remediation or replacement of under-performing projects; (3) Identification of new translational opportunities The Core is fully dedicated to overseeing the conduct of the Lung Cancer SPORE program, and providing organization and resources for the entire program, enabling it to fulfill its objectives to rapidly translate basic science discoveries into clinical applications to benefit lung cancer patients.

总结/摘要 行政核心将执行行政、协调、数据共享和评价职能， 埃默里肺癌孢子，以确保研究项目，核心和试点项目的职业生涯 增强计划（CEP）和发展研究计划（DRP）表现最好。的 行政核心将在监测进展方面发挥关键作用， 表现不佳的项目，并根据需要用新的翻译项目取代它们。 为实现其目标，核心将履行以下行政职能：（1）提供必要的 （2）获取和分配机构配套资金，以促进 临床试验和试点项目;（3）管理CEP和DRP计划;（4）准备年度非竞争性 进度报告;（5）确保项目1和项目2中拟议的临床试验的伦理设计和实施 以及与项目1相关的伦理同伴研究。 核心还将承担以下协调职能：（1）每月安排和协调 SPORE研究者会议，以及年度务虚会;（2）安排与SPORE相关的研究者出差 研讨会和NCI转化科学会议;（3）计划和促进内部和 外部咨询委员会;（4）计划和促进每月执行委员会会议;（5）提供和 协调SPORE-SPORE和SPORE-NCI接口;（6）协调以确保所有 与NCI、FDA和其他联邦、地方和机构法规合作的研究项目;（7）让患者参与 提倡从病人的角度出发。 最后，核心小组将履行以下规划和评价职能： 评估研究进展;（2）补救或替换表现不佳的项目;（3） 识别新的翻译机会 核心完全致力于监督肺癌孢子计划的实施，并提供 组织和整个计划的资源，使其能够实现其目标，快速翻译基本 将科学发现转化为临床应用，使肺癌患者受益。