Integrated Cellular Imaging

集成细胞成像

• 批准号: 10595764
• 负责人: Suresh S Ramalingam
• 金额: $ 6.66万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-04-07 至 2023-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10595764
• 关键词: Accounting; Cancer Center Support Grant; Categories; Cells; Cellular biology; Collaborations; Consultations; Data; Data Storage and Retrieval; Drug Delivery Systems; Educational workshop; Ensure; Equipment; Faculty; Fostering; Funding; Grant; Hour; Human Resources; Image; Image Analysis; Imaging Techniques; Imaging technology; Individual; Infrastructure; Institutes; Journals; Knowledge; Laboratories; Maintenance; Malignant Neoplasms; Microscope; Mission; Molecular; Monitor; Pharmacology; Policies; Procedures; Publications; Publishing; Quality Control; Research; Research Personnel; Resolution; Resource Sharing; Schedule; Series; Services; Site; Technology; Time; Training; Training Support; Universities; Work; biomarker development; biomarker discovery; cancer cell; cancer imaging; cellular imaging; confocal imaging; fluorescence imaging; imaging approach; imaging capabilities; imaging system; improved; innovation; instrument; light microscopy; live cell imaging; member; microscopic imaging; mid-career faculty; multiphoton imaging; new technology; programs; tool; tumor diagnostic

INTEGRATED CELLULAR IMAGING SHARED RESOURCE – PROJECT SUMMARY/ABSTRACT The Integrated Cellular Imaging Shared Resource (Imaging SR; Category 1.33) provides state-of-the-art light microscopy and image analysis services to Winship investigators. Sixteen imaging systems are available at four sites established to serve Winship members throughout Emory’s main campus. Imaging SR services support Winship research efforts in biomarker discovery and development, cancer cell biology, tumor diagnostics, drug delivery, and molecular pharmacology. Imaging SR is utilized by members of all four Winship research programs, with 35-40 Winship members’ laboratories using Imaging SR each year during the current CCSG funding cycle. This utilization has supported work published in high impact journals and supported preliminary data leading to grants for investigators in all four programs. Winship members have access to novel technologies, including state-of-the-art multiphoton microscopes, super-resolution imaging, and live-cell imaging. Winship members receive services at a subsidized rate for Imaging SR usage. Winship supports dedicated Imaging SR staff (one faculty and three staff). To ensure these technologies are properly utilized, Imaging SR personnel provide comprehensive training sessions and consultation on experimental setup, execution, and analysis. Imaging SR personnel provide daily user assistance and perform maintenance on all equipment to ensure optimal image acquisition and analysis. The Imaging SR director has managed the Winship imaging shared resource facilities since 2005 and is a tenured associate professor with an NCI-funded laboratory. The mean total hourly usage by Winship members during the current funding cycle has been 3,486 hours/year, representing 52% of overall Imaging SR utilization by Winship members.

集成细胞成像共享资源-项目摘要/摘要 集成细胞成像共享资源(成像SR；1.33类)提供最先进的光线 为Winship调查人员提供显微镜和图像分析服务。16个成像系统在4个月内可用 为埃默里大学主校区内的Winship会员服务而设立的网站。映像SR服务支持 Winship致力于生物标记物的发现和开发、癌细胞生物学、肿瘤诊断、药物 递送和分子药理学。Winship的所有四个研究项目的成员都使用了成像SR， 在CCSG当前的资助周期内，每年有35-40个Winship成员实验室使用Imagine SR。 这种利用支持了在高影响力期刊上发表的工作，并支持了导致以下结果的初步数据 对所有四个项目中的调查人员的拨款。Winship会员可以使用新技术，包括 最先进的多光子显微镜、超分辨率成像和活细胞成像。Winship会员 按影像服务请求使用率的补贴费率接受服务。Winship支持专门的成像SR工作人员(1名 教职员工和三名工作人员)。为确保这些技术得到正确利用，成像SR人员提供 关于实验设置、执行和分析的全面培训课程和咨询。成像SR 人员为用户提供日常帮助，并对所有设备进行维护，以确保最佳形象 获取和分析。图像SR总监已管理Winship图像共享资源设施 自2005年以来，他是NCI资助的实验室的终身副教授。每小时的平均总使用量 Winship成员在当前资金周期中的工作时间为3486小时/年，占总时长的52% 对Winship成员的SR利用率进行映像。