Developmental Funds

发展基金

• 批准号: 10627511
• 负责人: Suresh S Ramalingam
• 金额: $ 44.53万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-04-07 至 2028-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10627511
• 关键词: Acceleration; Achievement; Address; Award; Back; Cancer Center Support Grant; Caring; Catchment Area; Center for Translational Science Activities; Clinical Investigator; Clinical Investigator Award; Clinical Oncology; Clinical Research; Clinical Trials; Communication; Communities; County; Custom; Data; Development; Disparity; Education; Ensure; First Independent Research Support and Transition Awards; Fostering; Funding; Goals; Grant; Growth; Health Disparities Research; Institution; Investigation; Investments; Journals; Leadership; Malignant Neoplasms; Malignant neoplasm of lung; Malignant neoplasm of thorax; Mission; Monitor; Mutate; Nature; Outcome; Patients; Peer Review; Performance; Philanthropic Fund; Pilot Projects; Process; Program Effectiveness; Program Evaluation; Publications; Reporting; Research; Research Personnel; Research Project Grants; Research Support; Resource Sharing; Resources; Risk Factors; Rural; STK11 gene; Science; Seminal; Standardization; Strategic Planning; Study Section; Surveys; Technology; Therapeutic Agents; Time; Tobacco-Related Carcinoma; Training and Education; Translating; United States National Institutes of Health; Universities; administrative database; anticancer research; cancer education; cancer immunotherapy; career; career development; innovation; malignant breast neoplasm; member; mid-career faculty; multidisciplinary; neoplasm registry; novel; oral HPV-positive head and neck cancers; programmed cell death protein 1; programs; prostate cancer risk; research and development; targeted agent; targeted treatment; technology platform; therapy development

PROJECT SUMMARY/ABSTRACT DEVELOPMENTAL FUNDS Winship Cancer Institute of Emory University (Winship) utilizes CCSG developmental funds in combination with philanthropic and institutional funds to drive strategic priorities and foster innovative cancer research. During the current cycle, funds were utilized to support two developmental shared resources: the Winship Data and Technology Applications Shared Resource (Data SR) and the Intervention Development, Dissemination, and Implementation Shared Resource (Dissemination SR). Both have advanced to full shared resources in this application. Funds were also used to support the Winship Invest$ pilot grant program. Winship Invest$ follows bi-annual funding cycles and a standardized peer-review process. A custom technology platform is utilized to manage the pilot grant program. This platform is integrated with the Winship administrative database and integrates funding, outcomes, and membership data. It is also used to manage documents, member surveys, and the review process. Winship Administration has established post-award processes to monitor funds and provide reports for leadership evaluation of program effectiveness. During the current funding period, CCSG developmental funds ($900,000) were awarded to 15 pilot projects and resulted in receipt of $2.6 million of external funding to date. CCSG funded awards from prior period (2013-2017, 24 awards, $778,000) resulted in $14.4 million external funding with average time of 30 months to first funding after award start date. Similar growth is anticipated for pilot funds from the current funding period. Winship also distributed $5.1 million in philanthropic, institutional, and other peer-reviewed funds during the reporting period for a total of $6 million allocated to 122 pilot awards and leading to $16.4 million in external funding. Findings from CCSG-funded research have been disseminated in high impact journals such as Nature, Nature Cancer, Nature Communications, and Journal of Clinical Oncology. Winship developmental funds have resulted in other noteworthy outcomes, such as the advancement of multidisciplinary team science research, career development for junior investigators, health disparities research, and performance of investigator-initiated clinical research. This competitive renewal requests developmental funds for continued support of Winship Invest$ with plans to fund 15-20 pilot grants with award amounts of $50,000 to $100,000 each. To build a pipeline of clinical trials development expertise, Winship also plans to fund one early-stage clinical investigator award per year with each award providing two years of support. Developmental funds in combination with institutional and philanthropic funds are a critical resource for the Executive Director and the leadership team to strategically support innovative research ideas and develop new research themes. These funds will enable Winship to continue its growth as a transformative leader integrating cancer research, education, care, and community impact to achieve its mission.

项目摘要/摘要 发展基金 埃默里大学温希普癌症研究所(温希普)利用CCSG发展基金与 慈善和机构基金，以推动战略优先事项和促进创新的癌症研究。在.期间 在本周期内，资金用于支持两项发展共享资源：Winship数据和 技术应用共享资源(Data SR)及其干预开发、传播和 实施共享资源(传播SR)。这两家公司都已升级到完全共享的资源 申请。资金还用于支持Winship Invest$Pilot赠款计划。Winship投资美元如下 每两年一次的供资周期和标准化的同行审查程序。利用定制技术平台 管理试点拨款计划。该平台与Winship管理数据库集成在一起， 集成资金、结果和成员数据。它还用于管理文档、成员调查、 以及审查过程。Winship Administration建立了获奖后流程，以监测资金和 为领导对项目有效性的评估提供报告。在本供资期间，CCSG 向15个试点项目发放了发展基金(90万美元)，并收到了260万美元 到目前为止，外部资金。CCSG资助的前期奖励(2013-2017年，24项奖励，778,000美元)导致 1,440万美元的外部资金，平均30个月到授标开始日期后的第一笔资金。类似 预计试点资金将从当前供资期间开始增长。Winship还分发了510万美元 在本报告所述期间，慈善基金、机构基金和其他同行审查基金共计600万美元 分配给122个试点奖项，获得1640万美元的外部资金。CCSG资助的调查结果 研究已在影响较大的期刊上传播，如《自然》、《自然癌症》、《自然》 和临床肿瘤学杂志。Winship发展基金已经导致了其他 值得注意的成果，如推进多学科团队科学研究、职业发展 对于初级研究人员，健康差异研究，以及由调查人员发起的临床研究的表现。 这项竞争性续签要求发展基金继续支持Winship Invest$，并计划 资助15-20笔试点赠款，每笔奖励金额为50,000至100,000美元。建立一条临床试验管道 开发专业知识，Winship还计划每年资助一个早期临床研究人员奖， 提供两年支持的奖励。发展基金与机构和慈善相结合 资金是执行主任和领导团队从战略上支持创新的关键资源 研究思路，开拓新的研究主题。这些资金将使Winship能够继续作为 集癌症研究、教育、护理和社区影响于一体的变革性领导者，以实现其使命。