Research Training in Allergy and Clinical Immunology

过敏和临床免疫学研究培训

基本信息

  • 批准号:
    10686797
  • 负责人:
  • 金额:
    $ 44.39万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2022
  • 资助国家:
    美国
  • 起止时间:
    2022-08-19 至 2027-07-31
  • 项目状态:
    未结题

项目摘要

Abstract The goal of this project is to develop innovative physicians and PhD scientists trained in the latest methods of laboratory, translational and clinical research and fully prepared to pursue independent research careers investigating critical issues in Allergy and Immunology (A/I). For over 40 years this program has produced leaders in the field of A/I. This application maintains the training collaboration established between the complementary A/I training programs at Duke University and The University of North Carolina Chapel Hill (UNC). The combined strength of their A/I programs and their respective Universities create an ideal venue for training the next generation of A/I investigators. This proposal continues a highly innovative program for both physicians and PhD trained scientists in translational research in immune- based diseases. These goals will be accomplished through 1) formal courses in clinical research design, 2) rigorous training in basic immunology and 3) a structured mentorship program. Our research emphasis areas are designed to address these future needs in the field: 1) Human Immune Response to Pathogens, 2) Immunobiology of Food Allergy and 3) Pathobiology of Asthma, Respiratory and Allergic Disease. Mentors were selected from highly integrated and focused programs currently in place at Duke and UNC who demonstrated research productivity. Additionally, in this cycle we will bring an increased focus to Diversity, Equity and Inclusion as well as the mentor development of junior faculty who will become future established mentors. This application requests support for five trainees each year. Fulfillment of the program's objective would directly or indirectly serve to meet two urgent medical needs: 1) the need for more full-time researchers and teachers of allergy and clinical immunology in medical schools throughout the country and 2) the need for more physicians trained in the specific care of patients with allergic and immunologic disorders.
摘要 该项目的目标是培养创新的医生和博士科学家在最新的方法, 实验室,转化和临床研究,并充分准备追求独立的研究事业 研究过敏和免疫学(A/I)的关键问题。40多年来,这个项目培养了 在A/I领域。此应用程序维护在互补的 A/I培训计划在杜克大学和北卡罗来纳州大学查佩尔山(北)。的 他们的A/I计划和各自的大学的综合实力创造了一个理想的培训场所 下一代人工智能调查员这一建议继续为双方高度创新的计划, 医生和博士在免疫疾病的转化研究方面培训科学家。这些目标 将通过1)临床研究设计的正式课程,2)基础知识的严格培训, 免疫学和3)结构化的导师计划。我们的研究重点领域旨在 满足该领域未来的需求:1)人类对病原体的免疫反应,2)免疫生物学 3)哮喘、呼吸道和过敏性疾病的病理生物学。导师们从 目前在杜克和杜克大学实施的高度综合和集中的项目, 生产力此外,在本周期中,我们还将更加关注多样性、公平性和包容性 作为初级教师的导师发展,他们将成为未来的导师。本申请 要求每年为五名受训人员提供支助。实现该计划的目标将直接或间接地 服务于满足两个迫切的医疗需求:1)需要更多的全职研究人员和过敏教师, 全国各地医学院的临床免疫学和2)需要更多的医生培训 过敏性和免疫性疾病患者的特殊护理。

项目成果

期刊论文数量(84)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
The epithelial cell-derived atopic dermatitis cytokine TSLP activates neurons to induce itch.
上皮细胞来源的特应性皮炎细胞因子 TSLP 激活神经元以诱发瘙痒。
  • DOI:
    10.1016/j.cell.2013.08.057
  • 发表时间:
    2013-10-10
  • 期刊:
  • 影响因子:
    64.5
  • 作者:
    Wilson SR;Thé L;Batia LM;Beattie K;Katibah GE;McClain SP;Pellegrino M;Estandian DM;Bautista DM
  • 通讯作者:
    Bautista DM
Pathogenesis of food allergy in the pediatric patient.
  • DOI:
    10.1007/s11882-012-0296-x
  • 发表时间:
    2012-12
  • 期刊:
  • 影响因子:
    5.5
  • 作者:
    Chin, Stacy;Vickery, Brian P.
  • 通讯作者:
    Vickery, Brian P.
Sublingual immunotherapy for peanut allergy: clinical and immunologic evidence of desensitization.
  • DOI:
    10.1016/j.jaci.2010.12.1083
  • 发表时间:
    2011-03
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Kim EH;Bird JA;Kulis M;Laubach S;Pons L;Shreffler W;Steele P;Kamilaris J;Vickery B;Burks AW
  • 通讯作者:
    Burks AW
What Is the Cause of the Chronic Erythematous Scaling Plaques on This 22-Month-Old Girl and Her Family?
这位 22 个月大的女孩及其家人出现慢性红斑鳞屑的原因是什么?
  • DOI:
    10.1177/0009922817738347
  • 发表时间:
    2018
  • 期刊:
  • 影响因子:
    1.6
  • 作者:
    Ro,Teresa;Sood,Amika;Kelly,KevinJ;Morrell,DeanS
  • 通讯作者:
    Morrell,DeanS
{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ monograph.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ sciAawards.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ conferencePapers.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ patent.updateTime }}

David B. Peden其他文献

Impact of Aeroallergen Sensitization on Asthma Control in African-American Teens with Persistent Asthma
空气过敏原敏化对患有持续性哮喘的非洲裔美国青少年哮喘控制的影响
  • DOI:
  • 发表时间:
    2021
  • 期刊:
  • 影响因子:
    0
  • 作者:
    A. Burbank;S. Grabich;Krista Todorich;Marcia Frye;C. Loughlin;Kelly Duncan;C. Robinette;K. Mills;David B. Peden;David Diaz;Michelle L. Hernandez
  • 通讯作者:
    Michelle L. Hernandez
Airway cells from atopic asthmatic patients exposed to ozone display an enhanced innate immune gene profile
  • DOI:
    10.1016/j.jaci.2011.11.007
  • 发表时间:
    2012-01-01
  • 期刊:
  • 影响因子:
  • 作者:
    Michelle Hernandez;Willie June Brickey;Neil E. Alexis;Rebecca C. Fry;Julia E. Rager;Baiming Zhou;Jenny P.Y. Ting;Haibo Zhou;David B. Peden
  • 通讯作者:
    David B. Peden
Effect of prednisone on woodsmoke-induced sputum inflammation in healthy volunteers: A randomized, placebo-controlled pilot study
  • DOI:
    10.1016/j.jacig.2024.100347
  • 发表时间:
    2025-02-01
  • 期刊:
  • 影响因子:
  • 作者:
    Terry L. Noah;Neil E. Alexis;William D. Bennett;Michelle L. Hernandez;Allison J. Burbank;Haolin Li;Haibo Zhou;Ilona Jaspers;David B. Peden
  • 通讯作者:
    David B. Peden
Global change, climate change, and asthma in children: Direct and indirect effects - A WAO Pediatric Asthma Committee Report
全球变化、气候变化与儿童哮喘:直接和间接影响——世界过敏组织儿科哮喘委员会报告
  • DOI:
    10.1016/j.waojou.2024.100988
  • 发表时间:
    2024-11-01
  • 期刊:
  • 影响因子:
    4.300
  • 作者:
    Peter N. Le Souëf;Yuichi Adachi;Eleni Anastasiou;Ignacio J. Ansotegui;Héctor A. Badellino;Tina Banzon;Cesar Pozo Beltrán;Gennaro D'Amato;Zeinab A. El-Sayed;Rene Maximiliano Gómez;Elham Hossny;Ömer Kalayci;Mário Morais-Almeida;Antonio Nieto-Garcia;David B. Peden;Wanda Phipatanakul;Jiu-Yao Wang;I-Jen Wan;Gary Wong;Paraskevi Xepapadaki;Nikolaos G. Papadopoulos
  • 通讯作者:
    Nikolaos G. Papadopoulos

David B. Peden的其他文献

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

{{ truncateString('David B. Peden', 18)}}的其他基金

Research Training in Allergy and Clinical Immunology
过敏和临床免疫学研究培训
  • 批准号:
    10493540
  • 财政年份:
    2022
  • 资助金额:
    $ 44.39万
  • 项目类别:
Project 4: Treatment of mucostasis and airways obstruction in asthma with a novel mucolytic
项目 4:用新型粘液溶解剂治疗哮喘粘膜淤积和气道阻塞
  • 批准号:
    10001602
  • 财政年份:
    2017
  • 资助金额:
    $ 44.39万
  • 项目类别:
Project 4: Treatment of mucostasis and airways obstruction in asthma with a novel mucolytic
项目 4:用新型粘液溶解剂治疗哮喘粘膜淤积和气道阻塞
  • 批准号:
    9356821
  • 财政年份:
    2017
  • 资助金额:
    $ 44.39万
  • 项目类别:
Gamma tocopherol chemoprevention of wood smoke PM2.5-induced airway inflammation
γ-生育酚化学预防木烟PM2.5引起的气道炎症
  • 批准号:
    9222012
  • 财政年份:
    2016
  • 资助金额:
    $ 44.39万
  • 项目类别:
Gamma tocopherol chemoprevention of wood smoke PM2.5-induced airway inflammation
γ-生育酚化学预防木烟PM2.5引起的气道炎症
  • 批准号:
    9883794
  • 财政年份:
    2016
  • 资助金额:
    $ 44.39万
  • 项目类别:
Gamma tocopherol chemoprevention of wood smoke PM2.5-induced airway inflammation
γ-生育酚化学预防木烟PM2.5引起的气道炎症
  • 批准号:
    9055845
  • 财政年份:
    2016
  • 资助金额:
    $ 44.39万
  • 项目类别:
Phase II studies of gamma tocopherol as an intervention for environmental asthma
γ-生育酚作为环境性哮喘干预措施的 II 期研究
  • 批准号:
    9269215
  • 财政年份:
    2013
  • 资助金额:
    $ 44.39万
  • 项目类别:
Phase II studies of gamma tocopherol as an intervention for environmental asthma
γ-生育酚作为环境性哮喘干预措施的 II 期研究
  • 批准号:
    8733697
  • 财政年份:
    2013
  • 资助金额:
    $ 44.39万
  • 项目类别:
Phase II studies of gamma tocopherol as an intervention for environmental asthma
γ-生育酚作为环境性哮喘干预措施的 II 期研究
  • 批准号:
    8598698
  • 财政年份:
    2013
  • 资助金额:
    $ 44.39万
  • 项目类别:
Phase II studies of gamma tocopherol as an intervention for environmental asthma
γ-生育酚作为环境性哮喘干预措施的 II 期研究
  • 批准号:
    9057036
  • 财政年份:
    2013
  • 资助金额:
    $ 44.39万
  • 项目类别:

相似海外基金

Treating Auditory Hypersensitivity in Autistic Children using Virtual Ambisonics
使用虚拟高保真音响治疗自闭症儿童的听觉过敏
  • 批准号:
    2887563
  • 财政年份:
    2023
  • 资助金额:
    $ 44.39万
  • 项目类别:
    Studentship
Early Menstrual Pain Impact on Multisensory Hypersensitivity
月经早期疼痛对多感觉超敏反应的影响
  • 批准号:
    10878181
  • 财政年份:
    2023
  • 资助金额:
    $ 44.39万
  • 项目类别:
Developing RNA Vaccines to Treat Peanut Hypersensitivity
开发治疗花生过敏的 RNA 疫苗
  • 批准号:
    10570339
  • 财政年份:
    2023
  • 资助金额:
    $ 44.39万
  • 项目类别:
The role of the gut microbiota in mediating pain hypersensitivity and other symptoms of fibromyalgia
肠道微生物群在介导疼痛过敏和纤维肌痛其他症状中的作用
  • 批准号:
    488080
  • 财政年份:
    2023
  • 资助金额:
    $ 44.39万
  • 项目类别:
    Operating Grants
Evaluation of disordered excitation coordination underlying gut hypersensitivity by functional micro-image analysis
通过功能微图像分析评估肠道超敏反应背后的紊乱兴奋协调
  • 批准号:
    23H02813
  • 财政年份:
    2023
  • 资助金额:
    $ 44.39万
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
Unraveling the role of satellite glial cells in sensory hypersensitivity in Fragile X syndrome
揭示卫星胶质细胞在脆性 X 综合征感觉超敏反应中的作用
  • 批准号:
    10752180
  • 财政年份:
    2023
  • 资助金额:
    $ 44.39万
  • 项目类别:
Midbrain pathways for visual hypersensitivity in neurofibromatosis type 1
1 型神经纤维瘤病视觉超敏反应的中脑通路
  • 批准号:
    10733781
  • 财政年份:
    2023
  • 资助金额:
    $ 44.39万
  • 项目类别:
The effectiveness and safety of treating dentine hypersensitivity with bioactive glasses
生物活性玻璃治疗牙本质过敏的有效性和安全性
  • 批准号:
    2898082
  • 财政年份:
    2023
  • 资助金额:
    $ 44.39万
  • 项目类别:
    Studentship
Elucidation of the molecular mechanism of activated B cells in the pathogenesis of hypersensitivity pneumonitis and its clinical significance.
阐明活化B细胞在过敏性肺炎发病中的分子机制及其临床意义。
  • 批准号:
    23K07622
  • 财政年份:
    2023
  • 资助金额:
    $ 44.39万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Rise-HP: Reimagining Interventions for Support and Education in Hypersensitivity Pneumonitis; A Stakeholder Engaged Intervention to Improve Health-Related Quality of Life
Rise-HP:重新构想对过敏性肺炎的支持和教育干预措施;
  • 批准号:
    10427983
  • 财政年份:
    2022
  • 资助金额:
    $ 44.39万
  • 项目类别:
{{ showInfoDetail.title }}

作者:{{ showInfoDetail.author }}

知道了