Center for Childhood Obesity Prevention - Metabolism and Bioenergetics Core

项目摘要 代谢和生物能量学核心（MBC）是儿童肥胖中心的关键研究核心 预防（CCOP）。MBC为CCOP提供尖端的生物医学研究服务 阿肯色州儿童研究所（阿克里）的调查人员说。我们的专业知识和重点是 稳定同位素技术和高分辨率呼吸测量法在基质研究中的应用 代谢和生物能量学。MBC的主要目标是支持早期阶段的CCOP调查人员， 研究的重点是发展，治疗和预防肥胖症， 仪器和专业知识，以执行研究的重点是改变代谢和生物能量学。这 包括研究设计、实施、生物样本分析以及数据分析， 解释。MBC将进一步指导研究人员使用关键的方法学方法来量化 代谢和生物能量学。我们的长期目标是将MBC转变为可持续的核心设施， 阿克里具有广泛的机构内外用户基础。

PROJECT SUMMARY The Metabolism and Bioenergetics Core (MBC) is a critical research core in the Center for Childhood Obesity Prevention (CCOP). The MBC make cutting-edge biomedical research services available to CCOP investigators at Arkansas Children’s Research Institute (ACRI). Our specific expertise and focus are the application of stable isotope technologies and high resolution respirometry to the study of substrate metabolism and bioenergetics. The primary goal of the MBC is to support early stage CCOP investigators in research focused on the development, treatment, and prevention of obesity by providing access to instrumentation and expertise to execute studies focused on altered metabolism and bioenergetics. This encompasses study design, implementation, biological sample analyses, as well as data analyses and interpretation. The MBC will further mentor investigators in key methodological approaches used to quantify metabolism and bioenergetics. Our long-term goal is to transition the MBC into a sustainable core facility at ACRI with broad intra- and extra-institutional user base.