Center for Childhood Obesity Prevention - Metabolism and Bioenergetics Core

项目总结 新陈代谢和生物能量学核心(MBC)是儿童肥胖中心的关键研究核心 预防(CCOP)。MBC为CCOP提供尖端生物医学研究服务 阿肯色州儿童研究所(ACRI)的研究人员。我们的具体专业知识和重点是 稳定同位素技术和高分辨率呼吸测量在底物研究中的应用 新陈代谢和生物能量学。MBC的主要目标是支持早期CCOP调查人员 研究集中在肥胖的发展、治疗和预防上，通过提供 仪器和专业知识，以执行重点研究变化的新陈代谢和生物能量学。这 包括研究设计、实施、生物样本分析以及数据分析和 释义。MBC将在用于量化的关键方法方法方面进一步指导调查人员 新陈代谢和生物能量学。我们的长期目标是将MBC转变为一个可持续的核心设施， ACRI拥有广泛的机构内和机构外用户基础。

PROJECT SUMMARY The Metabolism and Bioenergetics Core (MBC) is a critical research core in the Center for Childhood Obesity Prevention (CCOP). The MBC make cutting-edge biomedical research services available to CCOP investigators at Arkansas Children’s Research Institute (ACRI). Our specific expertise and focus are the application of stable isotope technologies and high resolution respirometry to the study of substrate metabolism and bioenergetics. The primary goal of the MBC is to support early stage CCOP investigators in research focused on the development, treatment, and prevention of obesity by providing access to instrumentation and expertise to execute studies focused on altered metabolism and bioenergetics. This encompasses study design, implementation, biological sample analyses, as well as data analyses and interpretation. The MBC will further mentor investigators in key methodological approaches used to quantify metabolism and bioenergetics. Our long-term goal is to transition the MBC into a sustainable core facility at ACRI with broad intra- and extra-institutional user base.