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Songmaking in a Group (SING): Music, Hallucinations & Predictive Coding

团体歌曲制作（SING）：音乐、幻觉

基本信息

批准号：
10704492
负责人：
PHILIP CORLETT
金额：
$ 48.78万
依托单位：
YALE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-09-10 至 2025-07-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10704492
关键词：
Analysis of Variance Auditory Hallucination Behavior Behavioral Belief Biological Assay Brain Cells Chemosensitization Clinical Trials Code Complex Computational Linguistics Computer Models Cues Distress Event Expectancy Family member Friends Functional disorder Future Hallucinations Hearing Impairment Individual Intervention Interview Laboratories Language Learning Light Linguistics Measures Meta-Analysis Mind Modeling Music Neurons Ownership Participant Perception Performance Periodicity Personal Satisfaction Persons Pharmacotherapy Phase Procedures Property Psychiatrist Psychiatry Psychoses Psychotherapy Psychotic Disorders Publishing Qualitative Research Quality of life Recording of previous events Recovery Research Research Personnel Rewards Scheme Self Concept Series Stimulus Symptoms Synaptic plasticity Task Performances Testing Toes Uncertainty Update Voice Work design expectation experience follow-up improved lexical musician peer power analysis psychotic symptoms severe mental illness social social engagement social learning theories

项目摘要

Abstract People with psychotic illnesses perceive and believe things about themselves, the outside world and other people that do not obtain. This can be very distressing for them, their family members and friends. Listening to and performing music can help mitigate this distress, but we do not know why. This project aims to find out. Perceiving and believing, about self and others, is achieved by making predictions and updating those predictions in light of new evidence, particularly if that new evidence is very reliable or precise. One way that music might help psychosis involves this precision. By making one set of predictions more precise—predictions about music— other predictions can change. This might be why we tap our toes or sing along to music we enjoy. We propose that experiencing more reliable predictions about ones’ actions (by singing) and other people (by singing along with them) will help to change the predictions that underwrite the symptoms of psychosis. We will test whether this is true in an initial R61 study, tracking the change in performance of a series of prediction-based tasks as a result of musical experience by prosecuting three specific aims: Specific Aim 1 will examine the impact of song- making in a group (SING) on conditioned hallucination task performance, a procedure that safely and reliably engenders hallucinations in the laboratory. We predict SING will reduce the number and mechanisms of hallucinations in the laboratory. Specific Aim 2 will examine how social learning changes with SING. Using a reputation learning task, we will measure social learning rates. We predict they will increase with SING. Specific Aim 3 will examine participants’ subjective experience of self-hood and how they change with SING using computational linguistic analysis. We predict SING will decrease linguistic markers of distress. If those studies prove successful, we will – in a follow-up R33 study – use metrics from the R61 to decompose the musical intervention into its key ingredients – asking whether it is important to be active (or merely passively experience music), and whether owning the music produced is important to its impact on precision of processing. These studies will help us refine whether, how and to whom we deliver musical intervention for serious mental illness.

摘要