Unraveling the molecular connections that link circadian rhythms and lipid metabolism

揭示昼夜节律和脂质代谢之间的分子联系

• 批准号: 10797879
• 负责人: XUEMIN WANG
• 金额: $ 7.25万
• 依托单位: UNIVERSITY OF MISSOURI-ST. LOUIS
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-03-10 至 2025-01-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10797879
• 关键词: Address; Administrative Supplement; Biological; Bioluminescence; Circadian Rhythms; Complex; DNA-Protein Interaction; Data; Detection; Equipment; Funding; Gel; Image; Image Enhancement; Label; Link; Lipids; Molecular; Research; Stains; fluorescence imaging; fluorophore; imaging system; instrument; lipid metabolism; molecular clock; multiplexed imaging; virtual

SUMMARY: This Administrative Supplement for Equipment requests supplemental funds to purchase a multiplex fluorescent imaging system. The ability to simultaneously image and analyze multiple fluorophores will greatly facilitate the proposed studies of lipid-protein-DNA interactions and enable us to address more complex biological questions. This instrument is an all-in-one imaging system to detect and analyze multiplex fluorescent labeling, chemiluminescence, bioluminescence, and virtually all common types of stains in gels, blots, and plates. The capacity of sensitive multiplexed imaging enhances research efficiency, data quantification, and reliability.

摘要：本《设备行政副刊》要求追加资金 购买一个多路荧光成像系统。能够同时成像和分析 多个荧光团将极大地促进拟议的脂质-蛋白质-DNA相互作用的研究 并使我们能够解决更复杂的生物学问题。这台仪器是一体机 用于检测和分析多重荧光标记、化学发光、 生物发光，以及凝胶、斑点和平板中几乎所有常见类型的污渍。容量 敏感的多路复用成像提高了研究效率、数据量化和 可靠性。