Intervention Development and Pilot Study to Prevent Untreated Native Hawaiian and Pacific Islander Opioid Use Disorders

预防未经治疗的夏威夷原住民和太平洋岛民阿片类药物使用障碍的干预措施开发和试点研究

• 批准号: 10376586
• 负责人: Andrew Makoto Subica
• 金额: $ 12.37万
• 依托单位: UNIVERSITY OF CALIFORNIA RIVERSIDE
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-07-15 至 2023-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10376586
• 关键词: Accident and Emergency department; Address; Adult; Affect; Age; Capital; Cessation of life; Communities; Coupled; Crime; Data; Development; Disease; Drug Screening; Economics; Ensure; Epidemic; Faculty; Feedback; Female; Focus Groups; Foundations; Funding; Future; Goals; Grant; Hawaii; Health; Health Professional; Healthcare Systems; Home; Intervention; Intervention Studies; Knowledge; Label; Legal; Length of Stay; Manuscripts; Medical center; Mentors; Mentorship; Methamphetamine; Methods; Modeling; National Institute of Drug Abuse; Native Hawaiian; Pacific Island Americans; Patients; Pharmaceutical Preparations; Pilot Projects; Policies; Policy Maker; Population; Prevention; Prevention Research; Public Health; Qualitative Methods; Race; Randomized Controlled Trials; Reporting; Research; Research Personnel; Research Training; Risk; Risk Factors; Shapes; Social Work; Structure; Substance Use Disorder; Testing; Training; Underserved Population; United States National Institutes of Health; Universities; Ursidae Family; Violence; Writing; authority; barrier to care; career; community based participatory research; convict; cost; design; drug testing; effective intervention; efficacy testing; epidemiology study; experience; follow-up; health disparity; health disparity populations; health organization; high risk; hospital services; improved; methamphetamine use; modifiable risk; novel; opioid mortality; opioid use disorder; overdose death; parent grant; patient screening; prevent; protective factors; sex; skills; social; substance use; substance use prevention; therapy development; trauma centers; treatment services

PROJECT ABSTRACT Pacific Islanders are an understudied U.S. racial group that endures severe disparities in substance use, and bears exceptionally high risk for methamphetamine use disorders (MUD) and resulting social, economic, and health harms. Yet, we know little about the causes and drivers of MUDs in Pacific Islander communities; restricting our ability to design effective interventions to prevent and treat MUDs in at-risk Pacific Islanders. To inform the development of effective methamphetamine prevention and treatment efforts for this understudied population, the goals of this Diversity Supplement are to improve our knowledge of Pacific Islander MUDs by qualitatively exploring the major risk and protective factors, and barriers to treatment, in Pacific Islanders with MUDs, and using this novel data to design a conceptual model of culturally grounded treatment-seeking intervention components for Pacific Islanders with MUDs. Specifically, in Year 1 of the study, the Diversity Supplement candidate—a female, early career social work faculty of Pacific Islander heritage—will conduct four focus groups of Pacific Islanders with MUDs to qualitatively investigate their treatment seeking barriers and facilitators, and risk and protective factors. In Year 2, the candidate will use her mentor’s established modified Delphi approach to design a conceptual model of MUD treatment-seeking intervention components for NHPIs and conduct 4 focus groups to validate and shape these components using feedback from lay NHPIs with MUDs. Building off the parent grant (which is focused on addressing opioid use disorders in Pacific Islanders), the goal of this supplement is to support the candidate in (1) conducting the first mixed methods study of MUDs among Pacific Islanders, and (2) obtaining intensive training and mentorship to become a leading authority on substance use prevention and intervention research with Pacific Islander populations. Supported by a mentoring team of established NIH-funded researchers in Pacific Islander substance use and health disparities, the candidate will gain critical skills in substance use epidemiological, prevention, and intervention research approaches, community-based participatory research, and manuscript and grant-writing. Building upon her structured research and training experiences on this NIDA Diversity Supplement, the candidate will apply for a NIDA K01 grant at the end of the funding period.

项目摘要 太平洋岛民是一个未被充分研究的美国种族群体，他们在物质使用方面存在严重差异， 并具有甲基苯丙胺使用障碍（MUD）的极高风险，并导致社会，经济， 和健康危害。然而，我们对太平洋岛民社区MUD的原因和驱动因素知之甚少; 限制了我们设计有效干预措施的能力，以预防和治疗处于危险中的太平洋岛民的MUD。到 告知有效的甲基苯丙胺预防和治疗工作的发展， 人口，本多样性补充材料的目标是通过以下方式提高我们对太平洋岛民MUD的了解 定性探讨太平洋岛民的主要风险和保护因素，以及治疗障碍， MUDs，并使用这些新的数据来设计一个基于文化的寻求治疗的概念模型 为患有重度抑郁症的太平洋岛民提供干预措施。具体而言，在研究的第一年，多样性 补充候选人-一名女性，太平洋岛民遗产的早期职业社会工作教师-将进行 四个重点小组的太平洋岛民与MUD定性调查他们的治疗寻求障碍 以及风险和保护因素。在第二年，候选人将使用她的导师的既定 改良德尔菲法设计MUD寻求治疗干预成分的概念模型 为NHPI和进行4个焦点小组，以验证和塑造这些组件使用反馈，从外行 带MUD的NHPIs。利用父母赠款（重点是解决太平洋岛屿国家的阿片类药物使用障碍）， 岛民），这个补充的目标是支持候选人在（1）进行第一混合方法 研究太平洋岛民中的MUD，以及（2）获得强化培训和指导，成为一名 太平洋岛民药物使用预防和干预研究的主要权威。 由美国国立卫生研究院资助的太平洋岛民物质使用研究人员组成的指导小组提供支持， 健康差异，候选人将获得物质使用流行病学，预防和 干预性研究方法、基于社区的参与性研究以及撰写手稿和赠款。 基于她在NIDA多样性补充方面的结构化研究和培训经验， 候选人将在资助期结束时申请NIDA K 01资助。