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Integrative Center for Precision Nutrition and Human Health

精准营养与人类健康综合中心

基本信息

批准号：
10799440
负责人：
Marla J Berry
金额：
$ 16.57万
依托单位：
UNIVERSITY OF HAWAII AT MANOA
依托单位国家：
美国
项目类别：
财政年份：
2022
资助国家：
美国
起止时间：
2022-03-20 至 2027-01-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10799440
关键词：
Administrative Supplement Award Biological Biological Sciences Cell Culture Techniques Cells Centers of Research Excellence Communities Community Outreach Core Facility Culture Media Dedications Development Electronic Mail Ensure Equipment Fluorescence Food Fostering Funding Future Gas Chromatography Gases Goals Grant Hawaii Health Health Benefit Human Individual Inductively Coupled Plasma Mass Spectrometry Infrastructure Liquid Chromatography Liquid substance Maintenance Mentors Modeling National Institute of General Medical Sciences Nutritional Science Outcome Periodicals Pilot Projects Plasma Preparation Research Research Personnel Research Project Grants Resources Roentgen Rays Saliva Sampling Schools Serum Shipping Sodium Soil Structure Surveys System Technology Tissues Trace Elements Training Training Programs Training Support Training and Education United States National Institutes of Health Universities Urine Vendor Water base career development college community based research community engagement cost data acquisition detection limit dietary supplements energy efficiency equipment acquisition instrument lipidomics manufacture nutrition precision nutrition response

项目摘要

PROJECT SUMMARY This proposal submission responds to a call for an Administrative Supplement to Existing NIH Grants for Equipment Purchase in which the Integrative Center for Precision Nutrition and Human Health (COBRE- Nutrition) at the University of Hawaiʻi at Mānoa aims to purchase a total reflection X-Ray fluorescence (TXRF) Spectrometer model S4 T-Star 200 manufactured by Bruker AXS LLC. The TXRF spectrometer is a state-of-the- art benchtop equipment to rapidly analyze ultra-trace element content in various samples, including biological fluids, food/supplements, cells, tissues, cell culture media, water, and other environmental samples, using small amounts of sample and with a detection limit at the ppb range. The specific aims of this Administrative Supplement request are: 1) to purchase a TXRF system to the UH community to be administered by a Core Facility inside the COBRE-Nutrition infrastructure; and 2) to provide access, training and technical support to researchers from the broad UH community in the use of the TXRF system. The TXRF will be housed in the Lipidomics Core Facility under the CRAFT structure of the COBRE-Nutrition. Proposed users include Research Project and Pilot Project Leaders of the COBRE-Nutrition, and multiple funded PIs from colleges and schools of the UH system. The COBRE-Nutrition benefits directly through expanding the breadth of several scientific project outcomes.

项目摘要本提案是对现有NIH赠款的行政补充呼吁的回应，精准营养与人类健康综合中心（COBRE- 夏威夷大学马诺阿分校的营养学）旨在购买全反射X射线荧光（TXRF）光谱仪型号S4 T-Star 200，由Bruker AXS LLC制造。TXRF光谱仪是一种最先进的台式设备，可快速分析各种样品中的超痕量元素含量，包括生物样品液体、食物/补充剂、细胞、组织、细胞培养基、水和其他环境样品，使用小样品量，检测限在ppb范围内。本行政法规的具体目标补充请求包括：1）向UH社区购买TXRF系统，由核心管理 COBRE-Nutrition基础设施内的设施;以及2）提供准入、培训和技术支持，来自广大UH社区的研究人员使用TXRF系统。TXRF将被安置在 COBRE-Nutrition的CRAFT结构下的脂质组学核心设施。建议用户包括研究 COBRE-Nutrition的项目和试点项目负责人，以及来自大学和学校的多个受资助的PI UH系统。COBRE-Nutrition通过扩大几个科学项目的范围而直接受益结果。