Texas A&M Center for Environmental Health Research

德克萨斯A

• 批准号: 10806557
• 负责人: Weston W Porter
• 金额: $ 4.53万
• 依托单位: TEXAS A&M UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-05-01 至 2025-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10806557
• 关键词: Address; Administrator; Affect; Area; Back; Collaborations; Communication; Communities; Community Services; Core Facility; Data; Data Science; Decision Making; Disease; Doctor of Philosophy; Ensure; Environment; Environmental Exposure; Environmental Health; Environmental Impact; Environmental Risk Factor; Faculty; Fostering; Health; Health Sciences; Human; In Vitro; Individual; Infrastructure; Institution; Integrative Medicine; Interdisciplinary Study; International; Investigation; Investments; Knowledge; Link; Mentors; Metabolism; Mission; Mus; Nature; Outcome; Persons; Pilot Projects; Policies; Policy Making; Population; Public Health; Recording of previous events; Regulation; Research; Research Personnel; Research Project Grants; Resources; Risk; Science; Technology; Texas; Translating; Translations; Underserved Population; Universities; Vision; base; career; career development; college; community engagement; educational atmosphere; innovation; instrumentation; interest; member; multidisciplinary; novel; outreach; programs; recruit; research facility; response; stressor; success; synergism; translational study

Overall ABSTRACT    The  vision  for  the  Texas  A&M  Center  for  Environmental  Health  Research  (TiCER)  is  to  nucleate  research  and  translational  activities  of  faculty  and  trainees  around  the  overarching  theme  “Enhancing  Public  Health  by  Identifying, Understanding and Reducing Adverse Environmental Health Risks.” This vision will be achieved by  building  on  Texas  A&M  University’s  ongoing  investments  in  people  and  facilities  and  a  history  of  state-­wide  outreach to community stakeholders, with a particular focus on underserved populations. Existing environmental  health  investments  at  Texas  A&M  provide  infrastructure  and  a  diverse  expertise  base  ready  to  catalyze  innovative  investigations  into  environmental  health  concerns  of  affected  communities  and  populations,  build  multidisciplinary  collaborations  among  Center  members  to  elucidate  mechanistic  links  between  environmental  exposures  and  adverse  health  outcomes,  and  translate  mechanistic  data  to  actionable  outcomes.  The  Center  will  continue  recent  successes  in  mentoring  junior  faculty,  recruitment  of  additional  established  faculty  into  environmental health research, and fostering a multi-­disciplinary, team-­oriented intellectual environment among  a core group of 54 members representing 11 colleges at Texas A&M. The thematic areas the Center will expand  upon  are:  1)  Stressors  to  Responses;;  2)  Environment  and  Metabolism;;  3)  Individuals  to  Populations;;  and  4)  Community, Regulation and Policy. The Center’s vision will be fulfilled through a highly integrated set of Facility  Cores.  The  Integrated  Health  Sciences  Facility  Core  will  support  bi-­directional  translation  with  a  human  translational studies component, a mouse translational studies component and an in vitro translational studies  component.  Three  technology-­integrating,  research  facility  cores  (Data  Science,  Bio  Science,  and  Chem  Science) will ensure Center member access to unparalleled instrumentation and resources of Texas A&M, a top  tier  public  research  university  with  extensive  outreach  throughout  the  state  of  Texas.  The  facility  cores  will  enhance  the  capacity,  breadth,  collaborative  nature,  and  impact  of  environmental  health  research.  The  Administrative Core and Pilot Project Program will facilitate the Center’s function by ensuring continuation of the  highest levels of institutional support, fostering career development and promoting multidisciplinary team science  that generates knowledge in areas of community concern. The Community Engagement Core will be a critical  vehicle for implementation of a multi-­prong strategy of the Center by serving as a bi-­directional portal to connect  Center members, affected communities and other stakeholders that builds on a strong tradition of Texas A&M  in public and community service statewide with a research focus on the health and environmental concerns of  underserved  populations.  Overall,  the  Center  will  expand  the  established  investigator  base  and  expertise  that  can be deployed to increase the impact of environmental health research in Texas and beyond.

整体的抽象

项目成果

Non-invasive evaluation of the equine gastrointestinal mucosal transcriptome.

马胃肠粘膜转录组的非侵入性评估。

• DOI: 10.1371/journal.pone.0229797
• 发表时间: 2020
• 期刊: PloS one
• 影响因子: 3.7
• 作者: Coleman,MichelleC;Whitfield-Cargile,Canaan;Cohen,NoahD;Goldsby,JenniferL;Davidson,Laurie;Chamoun-Emanuelli,AnaM;Ivanov,Ivan;Eades,Susan;Ing,Nancy;Chapkin,RobertS
• 通讯作者: Chapkin,RobertS

Butyrate-containing structured lipids inhibit RAC1 and epithelial-to-mesenchymal transition markers: a chemopreventive mechanism against hepatocarcinogenesis.

• DOI: 10.1016/j.jnutbio.2020.108496
• 发表时间: 2020-12
• 期刊: The Journal of nutritional biochemistry
• 作者: de Conti A;Tryndyak V;Heidor R;Jimenez L;Moreno FS;Beland FA;Rusyn I;Pogribny IP
• 通讯作者: Pogribny IP

Specificity Proteins (Sp) and Cancer.

• DOI: 10.3390/ijms24065164
• 发表时间: 2023-03-08
• 期刊: International journal of molecular sciences
• 影响因子: 5.6

Impact of Diabetes Self-Management Education on Psychological Distress and Health Outcomes Among African Americans and Hispanics/Latinos With Diabetes.

• DOI: 10.2337/ds18-0081
• 发表时间: 2019-11-01
• 期刊: Diabetes spectrum : a publication of the American Diabetes Association
• 作者: Pena-Purcell, Ninfa;Han, Gang;Ory, Marcia G
• 通讯作者: Ory, Marcia G

FoxO1 Deficiency Enhances Cell Proliferation and Survival Under Normoglycemia and Promotes Angiogenesis Under Hyperglycemia in the Placenta.

• DOI: 10.1016/j.labinv.2022.100017
• 发表时间: 2023-01
• 期刊: Laboratory investigation; a journal of technical methods and pathology
• 作者: Zehuan Ding;Naomi McCauley;Yushu Qin;Lauren Lawless;Shaodong Guo;Lanjing Zhang;Ke K. Zhang;Linglin Xie