Nonhuman Primate Testing Center for Evaluation of Somatic Cell Genome Editing Tools: Antibodies Supplement

非人类灵长类动物体细胞基因组编辑工具评估测试中心：抗体补充​​剂

• 批准号: 10827650
• 负责人: DENNIS J. HARTIGAN-O'CONNOR
• 金额: $ 24.12万
• 依托单位: UNIVERSITY OF CALIFORNIA AT DAVIS
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-04-14 至 2025-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10827650
• 关键词: Acceleration; Antibodies; California; Center for Translational Science Activities; Clinical Sciences; Collaborations; Communities; Ensure; Evaluation; Fostering; Future; Genome; Infrastructure; Primates; Research; Research Personnel; Resources; Technology; Testing; Translations; gene therapy; genome editing; human disease; nonhuman primate; somatic cell gene editing; support tools; synergism; tool

PROJECT SUMMARY / ABSTRACT The Nonhuman Primate Testing Center for Evaluation of Somatic Cell Genome Editing Tools supports studies with nonhuman primates that will advance the genome editing field, and significantly contributes to the future translation of these technologies for the treatment of human disease. The Nonhuman Primate Testing Center includes a robust team and partnerships that capitalize on major strengths including the California National Primate Research Center, Genome Center, and Clinical and Translational Science Center. The Nonhuman Primate Testing Center offers state-of-the-art capabilities for Somatic Cell Genome Editing (SCGE) investigators to conduct high quality research in nonhuman primates. The Testing Center leverages a supportive framework that has demonstrated a long-standing commitment to providing research opportunities and collaborations to investigators nationwide. Through this powerful infrastructure the Testing Center fosters partnerships with SCGE awardees through provision of expertise, resources, and collaborative opportunities that accelerate their research, and ensures synergism across the SCGE Consortium and with ongoing interactions with the Dissemination and Coordinating Center. This supplement supports a key collaborative project that will result in new opportunities with broad applications for the gene therapy and somatic cell genome editing fields, and will be conducted utilizing all of the capabilities of the Nonhuman Primate Testing Center for Evaluation of Somatic Cell Genome Editing Tools.

项目摘要/摘要 非人灵长类测试中心体细胞基因组编辑工具支持研究 这将推动基因组编辑领域的发展，并对未来做出重大贡献 将这些技术转化为治疗人类疾病的技术。非人灵长类动物检测中心 包括一个强大的团队和合作伙伴关系，利用主要优势，包括加州国家 灵长类研究中心、基因组中心、临床和翻译科学中心。非人类 灵长类检测中心提供最先进的体细胞基因组编辑(SCGE)功能 研究人员在非人类灵长类动物身上进行高质量的研究。测试中心利用 表现出长期致力于提供研究机会的支持性框架 以及与全国调查人员的合作。通过这一强大的基础设施，考试中心促进 通过提供专业知识、资源和协作机会，与SCGE获奖者建立伙伴关系 这加快了他们的研究，并确保了整个SCGE联盟和正在进行的 与传播和协调中心的互动。本附录支持一项关键的协作 将为基因治疗和体细胞带来广泛应用的新机遇 基因组编辑领域，并将利用非人灵长类测试的所有能力进行 体细胞基因组编辑工具评估中心。