LATC Collaborative Project

LATC合作项目

• 批准号: 10662828
• 负责人: DENNIS J. HARTIGAN-O'CONNOR
• 金额: $ 36.59万
• 依托单位: UNIVERSITY OF CALIFORNIA AT DAVIS
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-07-11 至 2023-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10662828
• 关键词: California; Center for Translational Science Activities; Clinical Sciences; Collaborations; Communities; Ensure; Evaluation; Fostering; Funding; Future; Genome; Infrastructure; Instruction; Primates; Research; Research Personnel; Resources; Technology; Testing; Translations; United States National Institutes of Health; genome editing; human disease; nonhuman primate; somatic cell gene editing; support tools; synergism; tool

PROJECT SUMMARY / ABSTRACT The Nonhuman Primate Testing Center for Evaluation of Somatic Cell Genome Editing Tools supports studies with nonhuman primates that will advance the genome editing field, and significantly contributes to the future translation of these technologies for the treatment of human disease. The Nonhuman Primate Testing Center includes a robust team and partnerships that capitalize on major strengths including the California National Primate Research Center, Genome Center, and Clinical and Translational Science Center. The Nonhuman Primate Testing Center offers state-of-the-art capabilities for Somatic Cell Genome Editing (SCGE) awardees to conduct high quality research in nonhuman primates. The Testing Center leverages a supportive framework that has demonstrated a long-standing commitment to providing research opportunities and collaborations to investigators nationwide. Through this powerful infrastructure the Testing Center fosters partnerships with SCGE awardees through provision of expertise, resources, and collaborative opportunities that accelerate their research, and ensures synergism across the SCGE Consortium and with ongoing interactions with the Dissemination and Coordinating Center. This supplement supports projects for investigators funded through the Consortium and will provide all of the benefits and capabilities of the Nonhuman Primate Testing Center for Evaluation of Somatic Cell Genome Editing Tools.

项目总结/摘要 体细胞基因组编辑工具评估非人类灵长类动物测试中心支持研究 与非人类灵长类动物合作，将推动基因组编辑领域的发展，并为未来做出重大贡献。 将这些技术转化为人类疾病的治疗。非人类灵长类动物检测中心 包括一个强大的团队和合作伙伴关系，利用主要优势，包括加州国家 灵长类动物研究中心、基因组中心、临床和转化科学中心。非人 灵长类动物测试中心为体细胞基因组编辑（SCGE）获奖者提供最先进的功能 对非人类灵长类动物进行高质量的研究。测试中心利用支持性框架 这表明了长期致力于提供研究机会和合作， 全国各地的调查员。通过这一强大的基础设施，测试中心与 SCGE获奖者通过提供专业知识，资源和合作机会，加速他们的 研究，并确保整个SCGE联盟的协同作用，并与正在进行的互动， 传播和协调中心。本补充文件支持通过以下方式供资的调查员项目： 联盟，并将提供所有的好处和能力的非人类灵长类动物测试中心， 体细胞基因组编辑工具的评价。