LATC Collaborative Project

LATC合作项目

• 批准号: 10662828
• 负责人: DENNIS J. HARTIGAN-O'CONNOR
• 金额: $ 36.59万
• 依托单位: UNIVERSITY OF CALIFORNIA AT DAVIS
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-07-11 至 2023-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10662828
• 关键词: California; Center for Translational Science Activities; Clinical Sciences; Collaborations; Communities; Ensure; Evaluation; Fostering; Funding; Future; Genome; Infrastructure; Instruction; Primates; Research; Research Personnel; Resources; Technology; Testing; Translations; United States National Institutes of Health; genome editing; human disease; nonhuman primate; somatic cell gene editing; support tools; synergism; tool

PROJECT SUMMARY / ABSTRACT The Nonhuman Primate Testing Center for Evaluation of Somatic Cell Genome Editing Tools supports studies with nonhuman primates that will advance the genome editing field, and significantly contributes to the future translation of these technologies for the treatment of human disease. The Nonhuman Primate Testing Center includes a robust team and partnerships that capitalize on major strengths including the California National Primate Research Center, Genome Center, and Clinical and Translational Science Center. The Nonhuman Primate Testing Center offers state-of-the-art capabilities for Somatic Cell Genome Editing (SCGE) awardees to conduct high quality research in nonhuman primates. The Testing Center leverages a supportive framework that has demonstrated a long-standing commitment to providing research opportunities and collaborations to investigators nationwide. Through this powerful infrastructure the Testing Center fosters partnerships with SCGE awardees through provision of expertise, resources, and collaborative opportunities that accelerate their research, and ensures synergism across the SCGE Consortium and with ongoing interactions with the Dissemination and Coordinating Center. This supplement supports projects for investigators funded through the Consortium and will provide all of the benefits and capabilities of the Nonhuman Primate Testing Center for Evaluation of Somatic Cell Genome Editing Tools.

项目摘要/摘要 非人灵长类测试中心体细胞基因组编辑工具支持研究 这将推动基因组编辑领域的发展，并对未来做出重大贡献 将这些技术转化为治疗人类疾病的技术。非人灵长类动物检测中心 包括一个强大的团队和合作伙伴关系，利用主要优势，包括加州国家 灵长类研究中心、基因组中心、临床和翻译科学中心。非人类 灵长类检测中心为体细胞基因组编辑(SCGE)获奖者提供最先进的功能 在非人类灵长类动物中进行高质量的研究。测试中心利用一个支持性框架 这表明了提供研究机会和合作的长期承诺 全国范围内的调查人员。通过这一强大的基础设施，考试中心与 SCGE获奖者通过提供专业知识、资源和协作机会来加速其 研究，并确保在整个SCGE联盟内以及与 传播与协调中心。本附录支持通过以下方式资助的调查人员的项目 该联盟将提供非人灵长类测试中心的所有好处和能力 体细胞基因组编辑工具的评价。