Augmented mapping of the Extreme Heat and Cold Events (EHE/ECE) at continental scale with cloud-based computing
Augmented mapping of the Extreme Heat and Cold Events (EHE/ECE) at continental scale with cloud-based computing
批准号:
10826885
负责人:
Francesca Dominici
金额:
$23.02万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2022
资助国家:
美国
项目状态:
未结题
起止时间:
2022-06-01 至 2025-05-31
关键词:
AlgorithmsAlzheimer&aposs DiseaseAlzheimer&aposs disease related dementiaAmericanAreaCardiovascular DiseasesCensusesClimateCloud ComputingCommunitiesComplexComputing MethodologiesDataDatabasesDedicationsDevelopmentEventExposure toGeographyHealthHigh Performance ComputingHybridsInfrastructureLinkLong-Term EffectsMapsMemoryMental disordersMethodologyMethodsModelingMonitorOutcomePatientsPerformancePopulationReproducibilityResearchResourcesRespiratory DiseaseServicesSpecific qualifier valueTemperatureTestingTimeUnited StatesWeatherclimate datacluster computingcohortcomputing resourcesdata pipelineextreme heatextreme weatherimprovedparallel computerparent grantpatient populationscale uptemporal measurementtoolweather stations
中文摘要
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英文摘要
Project Summary/Narrative
Extreme heat and cold events (EHE/ECE) have been linked to a range of adverse health outcomes from
exacerbated pre-existing conditions to mental illness and respiratory and cardiovascular disease Previous
research has often determined the areas and population impacted by EHE/ECE through simplistic methods
that assign temperature data from the closest weather station to the population being studied (e.g., a census
tract or postal zipcode). Our preliminary analysis has demonstrated that dynamic spatial-temporal
methodologies significantly alleviate misclassifications that tend to occur in conventional approaches.
Implementing more sophisticated models with higher spatial and temporal resolution can pose computational
complexity which hinders application and scalability of the dynamic models. Here we propose a hybrid method
to leverage cloud computing resources to streamline and scale up EHE/ECE identification workflows with
improved specification to help configuration of on-premises computing. Aim 1: Improving scalability and
computational efficiency of detecting extreme climate events in-cloud versus on-premises computing We will
develop and implement computational methodologies to (1) scale up the spatial interpolation methods at
continental scale using parallel and distributed computing algorithms, (2) monitor and assess the performance
of these algorithms in terms of computational time, memory allocation and storage resources compared to the
dedicated server utilization and conventional High-Performance Computing (HPC) approach.We hypothesize
that cloud computing will improve efficiency of current methods which have been implemented on on-premises
computing infrastructure using all-in memory solutions and serialized data pipeline. We will leverage
efficiencies of spatially enabled databases along with DevOps tools and services such as containerization, and
automated deployment to streamline our research workflows. Aim 2: Improving accuracy and robustness of
extreme climate events identification in-cloud versus on-premises computing We will assess the robustness of
dynamic EHE/ECE delineation methods when applied to heterogeneous climatological data at continental
geographies and beyond. Specifically, we will evaluate the extent to which cloud computing improves the
accuracy of the spatial-temporal methods in identifying populations and areas impacted by EHE/ECE using
different model parameterization scenarios. We hypothesize that cloud computing will improve the accuracy
and robustness of EHE/ECE identification methods by (1) facilitating development of more complex models
that take into account additional environmental variables, (2) by streamlining reproducibility practices that
enables the wider scientific community to test and validate the models at multiple scales that results in more
reliable models
期刊论文(4)
专著(0)
科研奖励(0)
会议论文
DOI:
10.1007/s00125-023-06001-7
发表时间:
2023-12
期刊:
DIABETOLOGIA
影响因子:
8.2
作者:
[Tian, Caiwei, Buerki, Charlyne, Westerman, Kenneth E., Patel, Chirag J.]
通讯作者:
Patel, Chirag J.
DOI:
10.1038/s43856-023-00271-3
发表时间:
2023-03-30
期刊:
COMMUNICATIONS MEDICINE
影响因子:
--
作者:
[Tangirala, Sivateja, Tierney, Braden T, Patel, Chirag J]
通讯作者:
Patel, Chirag J
DOI:
10.1016/j.envres.2023.116984
发表时间:
2023-08
期刊:
Environmental research
影响因子:
8.3
作者:
[P. Fard;M. Chung;Hossein Estiri;C. Patel]
通讯作者:
P. Fard;M. Chung;Hossein Estiri;C. Patel
CAFÉ: a Research Coordinating Center to Convene, Accelerate, Foster, and Expand the Climate Change and Health Community of Practice
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批准号:10689581
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项目类别:
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资助金额:$674.78万
-
财政年份:2023
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负责人:Francesca Dominici
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依托单位:
Statistical methods to characterize causal mechanisms by which air pollution affects the recurrence of cardiovascular events
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批准号:10660281
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项目类别:
-
资助金额:$179.01万
-
财政年份:2023
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负责人:Francesca Dominici
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依托单位:
The confluence of extreme heat cold on the health and longevity of an Aging Population with Alzheimers and related Dementia
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批准号:10448053
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项目类别:
-
资助金额:$238.55万
-
财政年份:2022
-
负责人:Francesca Dominici
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依托单位:
Relationship Between Multiple Environmental Exposures and CVD Incidence and Survival: Vulnerability and Susceptibility
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批准号:10163485
-
项目类别:
-
资助金额:$24.67万
-
财政年份:2020
-
负责人:Francesca Dominici
-
依托单位:
Integrating Air Pollution Prediction Models: Uncertainty Quantification and Propagation in Health Studies
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批准号:9885918
-
项目类别:
-
资助金额:$63.29万
-
财政年份:2020
-
负责人:Francesca Dominici
-
依托单位:
Integrating Air Pollution Prediction Models: Uncertainty Quantification and Propagation in Health Studies
-
批准号:10543137
-
项目类别:
-
资助金额:$60.91万
-
财政年份:2020
-
负责人:Francesca Dominici
-
依托单位:
Integrating Air Pollution Prediction Models: Uncertainty Quantification and Propagation in Health Studies
-
批准号:10330579
-
项目类别:
-
资助金额:$63.07万
-
财政年份:2020
-
负责人:Francesca Dominici
-
依托单位:
Relationship Between Multiple Environmental Exposures and CVD Incidence and Survival: Vulnerability and Susceptibility
-
批准号:10058839
-
项目类别:
-
资助金额:$64.26万
-
财政年份:2017
-
负责人:Francesca Dominici
-
依托单位:
Relationship Between Multiple Environmental Exposures and CVD Incidence and Survival: Vulnerability and Susceptibility
-
批准号:10310468
-
项目类别:
-
资助金额:$64.3万
-
财政年份:2017
-
负责人:Francesca Dominici
-
依托单位:
STATISTICAL COMPUTING CORE
-
批准号:8754136
-
项目类别:
-
资助金额:$9.14万
-
财政年份:2014
-
负责人:Francesca Dominici
-
依托单位:
A Translational Framework for Methodological Rigor to Improve Patient Centered Ou
-
批准号:8719901
-
项目类别:
-
资助金额:$14.92万
-
财政年份:2013
-
负责人:Francesca Dominici
-
依托单位:
A Translational Framework for Methodological Rigor to Improve Patient Centered Ou
-
批准号:8598569
-
项目类别:
-
资助金额:$15.83万
-
财政年份:2013
-
负责人:Francesca Dominici
-
依托单位:
Statistiscal methods for population health research on chemical mixtures
-
批准号:7990626
-
项目类别:
-
资助金额:$50.32万
-
财政年份:2009
-
负责人:Francesca Dominici
-
依托单位:
Statistiscal methods for population health research on chemical mixtures
-
批准号:7914360
-
项目类别:
-
资助金额:$47.31万
-
财政年份:2009
-
负责人:Francesca Dominici
-
依托单位:
Statistical Informatics for Cancer Research
-
批准号:8730551
-
项目类别:
-
资助金额:$68.76万
-
财政年份:2008
-
负责人:Francesca Dominici
-
依托单位:
Progress During the Current Funding Period
-
批准号:8589669
-
项目类别:
-
资助金额:$9.28万
-
财政年份:2008
-
负责人:Francesca Dominici
-
依托单位:
Statistical Informatics for Cancer Research
-
批准号:9098450
-
项目类别:
-
资助金额:$69.33万
-
财政年份:2008
-
负责人:Francesca Dominici
-
依托单位:
Program as an Integrated Effort
-
批准号:8589665
-
项目类别:
-
资助金额:$7.46万
-
财政年份:2008
-
负责人:Francesca Dominici
-
依托单位:
Methods for Comparative Effectiveness Research in Cancer
-
批准号:8589660
-
项目类别:
-
资助金额:$22.42万
-
财政年份:2008
-
负责人:Francesca Dominici
-
依托单位:
Statistical Methods for Analysis of Next Generation Sequencing Data in Gen
-
批准号:8589661
-
项目类别:
-
资助金额:$14.28万
-
财政年份:2008
-
负责人:Francesca Dominici
-
依托单位: