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Supplement for an intervention to increase HIV Testing Uptake among Adolescents and Young Adults

增加青少年和年轻人艾滋病毒检测率的干预措施的补充

基本信息

批准号：
10881477
负责人：
Amanda Derryck Castel
金额：
$ 10万
依托单位：
MEDIA REZ, LLC
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-08-01 至 2025-03-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10881477
关键词：
Adolescent and Young Adult Age Attitude Behavior Therapy Caring Development Educational Materials Enrollment Ensure Environment Focus Groups HIV HIV Infections HIV Seronegativity HIV risk Health education Human immunodeficiency virus test Incentives Intervention Knowledge Learning Life Location Medical Modeling Nature Patient Self-Report Phase Play Population Populations at Risk Prevention Preventive care Public Health Randomized Randomized, Controlled Trials Risk Risk Assessment Risk Behaviors Risk Reduction Behavior Technology Testing Time Treatment Efficacy Video Games Youth behavior change cost disorder prevention efficacy evaluation efficacy testing evidence base experience field study innovation multidisciplinary novel prevention service quality assurance recruit sex sexually active simulation game social media testing services testing uptake usability user-friendly

项目摘要

This supplement is to cover expenses that could not have been foreseen at the time of application, including recruiting costs and incentive costs. The study aims to assess the acceptability, usability, and efficacy of using state-of-the-art social media and game technology to increase HIV testing among adolescents and young adults (AYA) ages 13-24. Rates of HIV testing among AYA are low, resulting in high proportions of AYA who are unaware of their HIV infection. Since many AYA are highly engaged with social media and games, these technologies may hold the key to reaching this population. While previous behavior-change games have shown positive results by using the compelling nature of gameplay to make health education entertaining and shift attitudes towards disease prevention, this intervention proposes to incorporate a new innovation which changes the way video games are used to increase HIV testing and linkage to care. The intended result is a novel experience which plays like a game while prompting dialogue about HIV risk assessment, testing, and linkage to prevention in a manner that may be more acceptable to AYA compared to traditional public health messages. We have developed an AYA-informed game in which players can create characters like themselves, model different forms of dating and sex practices to learn the consequences in a simulated, non-health or life-threatening environment, and identify locations for HIV testing and prevention services. We seek to test the efficacy of this game and hypothesize that its use will result in increased HIV testing and lead to a reduction in risky behaviors among AYA at risk for HIV. In this Phase II application, our multidisciplinary team recruited AYA for iterative focus groups to confirm the acceptability of additional game enhancements. We then conducted pilot field testing of the game intervention among AYA (n=10) to ensure usability, acceptability and to conduct quality assurance testing. We now plan to conduct a randomized controlled trial to determine the efficacy of the intervention on HIV testing uptake. We will enroll 300 sexually active HIV negative AYA and randomize them to receive either the life-simulation game intervention or an app which contains HIV educational materials. We will compare self-reported HIV testing between the two study groups. Successful completion of these aims will demonstrate how this product may advance the effective implementation of an evidence-based behavioral intervention for increased HIV testing and linkage to preventive care among youth. Successful development of this core technology could also be revised to be applicable to other medical conditions.

这笔补助金将用于支付当时无法预见的费用。包括招聘成本和激励成本。该研究旨在评估使用最先进的社交媒体和游戏技术的可接受性、可用性和有效性在13-24岁的青少年和年轻人中增加艾滋病毒检测。艾滋病毒感染率 AYA中的检测率很低，导致AYA中不知道自己感染艾滋病毒的比例很高感染由于许多AYA高度参与社交媒体和游戏，这些技术可能是接触这些人群的关键虽然以前的行为改变游戏通过利用游戏的吸引力来进行健康教育，娱乐和改变对疾病预防的态度，这项干预措施建议，结合一项新的创新，改变了电子游戏被用来增加艾滋病毒的方式，检测和与护理的联系。预期的结果是一种像游戏一样的新奇体验同时促进关于艾滋病毒风险评估、检测以及与预防的联系的对话，与传统的公共卫生信息相比，这种方式可能更容易被AYA接受。我们已经开发了一个AYA知情的游戏中，玩家可以创建的字符，他们自己，模拟不同形式的约会和性行为，以了解其后果，模拟、非健康或危及生命的环境，并确定艾滋病毒检测的地点，预防服务。我们试图测试这个游戏的有效性，并假设它的使用将导致增加艾滋病毒检测，并导致AYA风险中的危险行为减少，艾滋病。在第二阶段的应用中，我们的多学科团队招募了AYA进行迭代聚焦小组，以确认额外的游戏增强的可接受性。然后我们进行了试点在AYA（n=10）中进行游戏干预的现场测试，以确保可用性、可接受性，进行质量保证测试。我们现在计划进行一项随机对照试验，确定干预措施对艾滋病毒检测的有效性。我们将招收300名活跃的艾滋病毒阴性AYA，并随机接受生活模拟游戏干预或包含艾滋病毒教育材料的应用程序。我们将比较自我报告两个研究组之间的艾滋病毒检测。成功实现这些目标将展示该产品如何促进有效实施基于证据的增加艾滋病毒检测的行为干预以及与青年预防保健的联系。这项核心技术的成功开发也可以修改，以适用于其他医疗条件。