The Icahn School of Medicine at Mount Sinai (ISMMS) EPPIC-Net Specialized Clinical Center

西奈山伊坎医学院 (ISMMS) EPPIC-Net 专业临床中心

基本信息

项目摘要

ABSTRACT (from the parent) The Icahn School of Medicine at Mount Sinai (ISMMS) is strongly-positioned to engage in the mission of the Early Phase Pain Investigation Clinical Network (EPPIC-Net), with the ISMMS Department of Neurology as the core of our hub and spokes structure. Our strengths include: (1) the large and diverse population we care for and have successfully recruited into clinical trials over several decades including patients with high impact pain syndromes such as chronic low back pain (CLBP), (2) our extensive clinical trials infrastructure, including close integration with the ISMMS CTSA and Trials Innovation Network (TIN), for which the PI of this proposal leads pain-related activities, and (3) a cadre of highly-experienced clinical trialists in multiple specialties with expertise across the range of studies EPPIC-Net will perform including mechanistic studies, detailed phenotyping of pain conditions, biomarker validation studies, and phase 2 clinical trials. We are deeply committed to using these strengths and our experienced leadership team in service of the EPPIC- Net mission which we strongly believe will ultimately produce the non-addictive pain treatments which our patients so desperately need. In order to ensure that our site and the entire EPPIC-Net structure is a success, our proposal has four specific aims: (1) to streamline and optimize rapid implementation of EPPIC-Net studies, exceeding the required minimum of 100 subjects recruited per year to EPPIC-Net studies; (2) to ensure access to patient populations with a wide range of pain disorders, including CLBP, using a hub and spokes model to ensure effective recruitment; (3) to provide the highest-quality protocol implementation, deep clinical phenotyping of pain disorders, and accurate and complete data collection; and (4) to work collaboratively with the EPPIC-Net Coordinating Centers and investigators from the NIH HEAL Partnership to assist with development/design of clinical trials and engage in EPPIC-Net leadership. In addition to these aims we will promote the visibility of EPPIC-Net within our institution and the larger pain research community, use our participation in EPPIC-Net as an opportunity to train junior investigators to become future pain clinical trials leaders and increase and disseminate knowledge about pain research throughout our network.
摘要(来自父级) 位于西奈山的伊坎医学院(ISMMS)处于有利地位,可以参与到 早期疼痛调查临床网络(EPPIC-NET),ISMMS神经内科为 我们的轮毂和辐条结构的核心。我们的优势包括:(1)我们关心的人口众多和多样化 并在几十年内成功地纳入临床试验,包括患有高度冲击性疼痛的患者 症状,如慢性下腰痛(CLBP),(2)我们广泛的临床试验基础设施,包括 与ISMMS CTSA和试验创新网络(TIN)的整合,本提案的PI领导该网络 与疼痛相关的活动,以及(3)具有专业知识的多个专科的经验丰富的临床试验人员队伍 EPPIC-Net将进行的研究范围包括机械学研究、疼痛的详细表型分析 条件、生物标记物验证研究和第二阶段临床试验。 我们坚定地致力于利用这些优势和我们经验丰富的领导团队为EPPIC服务- Net使命,我们坚信最终将产生非成瘾性疼痛治疗,我们的 病人是如此迫切需要。为了确保我们的网站和整个EPPIC-Net结构的成功, 我们的建议有四个具体目标:(1)精简和优化EPPIC-Net研究的快速实施, 超过要求的每年至少招募100名受试者参加EPPIC-Net研究;(2)确保获得 对于患有各种疼痛障碍的患者群体,包括CLBP,使用中枢和辐条模型来 确保有效招募;(3)提供最高质量的方案执行,深度临床表型 以及(4)与EPPIC网络合作 来自NIH Hear合作伙伴的协调中心和调查人员协助开发/设计 临床试验和参与EPPIC-Net领导。 除了这些目标外,我们还将促进EPPIC-Net在我们机构内的可见度和更大的痛苦 研究界,利用我们参与EPPIC-Net的机会培训初级调查人员 成为未来疼痛临床试验的领导者,增加和传播有关疼痛研究的知识 在我们的网络中。

项目成果

期刊论文数量(1)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Disparities in telehealth utilization in patients with pain during COVID-19.
  • DOI:
    10.1097/pr9.0000000000001001
  • 发表时间:
    2022-05
  • 期刊:
  • 影响因子:
    4.8
  • 作者:
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Jessica Robinson-Papp其他文献

Jessica Robinson-Papp的其他文献

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{{ truncateString('Jessica Robinson-Papp', 18)}}的其他基金

Effects of Vagal Dysfunction on Gastrointestinal and Inflammatory Pathways in HIV
迷走神经功能障碍对 HIV 胃肠道和炎症通路的影响
  • 批准号:
    9927114
  • 财政年份:
    2020
  • 资助金额:
    $ 20.13万
  • 项目类别:
Effects of Vagal Dysfunction on Gastrointestinal and Inflammatory Pathways in HIV
迷走神经功能障碍对 HIV 胃肠道和炎症通路的影响
  • 批准号:
    10819353
  • 财政年份:
    2020
  • 资助金额:
    $ 20.13万
  • 项目类别:
The Icahn School of Medicine at Mount Sinai (ISMMS) EPPIC-Net Specialized Clinical Center
西奈山伊坎医学院 (ISMMS) EPPIC-Net 专业临床中心
  • 批准号:
    10208322
  • 财政年份:
    2020
  • 资助金额:
    $ 20.13万
  • 项目类别:
Effects of Vagal Dysfunction on Gastrointestinal and Inflammatory Pathways in HIV
迷走神经功能障碍对 HIV 胃肠道和炎症通路的影响
  • 批准号:
    10356148
  • 财政年份:
    2020
  • 资助金额:
    $ 20.13万
  • 项目类别:
Effects of Vagal Dysfunction on Gastrointestinal and Inflammatory Pathways in HIV
迷走神经功能障碍对 HIV 胃肠道和炎症通路的影响
  • 批准号:
    10579307
  • 财政年份:
    2020
  • 资助金额:
    $ 20.13万
  • 项目类别:
Toward safer opioid prescribing for chronic pain in high risk populations: implementing the Centers for Disease Control Guideline (CDC) guideline in the primary care HIV clinic
为高危人群的慢性疼痛提供更安全的阿片类药物处方:在初级保健 HIV 诊所实施疾病控制中心 (CDC) 指南
  • 批准号:
    9753158
  • 财政年份:
    2017
  • 资助金额:
    $ 20.13万
  • 项目类别:
Autonomic neuropathy, gastrointestinal motility, and inflammation in HIV
HIV 的自主神经病变、胃肠道运动和炎症
  • 批准号:
    9110258
  • 财政年份:
    2015
  • 资助金额:
    $ 20.13万
  • 项目类别:
HIV-associated Neuropathy: Ethnic Disparities and Pathogenesis
HIV 相关神经病:种族差异和发病机制
  • 批准号:
    7910480
  • 财政年份:
    2009
  • 资助金额:
    $ 20.13万
  • 项目类别:
HIV-associated Neuropathy: Ethnic Disparities and Pathogenesis
HIV 相关神经病:种族差异和发病机制
  • 批准号:
    8303342
  • 财政年份:
    2009
  • 资助金额:
    $ 20.13万
  • 项目类别:
HIV-associated Neuropathy: Ethnic Disparities and Pathogenesis
HIV 相关神经病:种族差异和发病机制
  • 批准号:
    8512818
  • 财政年份:
    2009
  • 资助金额:
    $ 20.13万
  • 项目类别:

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Brain Mechanisms of Chronic Low-Back Pain: Specificity and Effects of Aging and Sex
慢性腰痛的脑机制:衰老和性别的特异性和影响
  • 批准号:
    10657958
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Relationships Between Pain-Related Psychological Factors, Gait Quality, and Attention in Chronic Low Back Pain
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  • 批准号:
    10679189
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结合多基因风险评分和生物心理社会测量的模型的开发和性能,以预测急性腰痛向慢性腰痛的转变
  • 批准号:
    478821
  • 财政年份:
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Racial and Socioeconomic Differences in Chronic Low Back Pain
慢性腰痛的种族和社会经济差异
  • 批准号:
    10656046
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Improving Function and Reducing Opioid Use for Patients with Chronic Low Back Pain in Rural Communities through Improved Access to Physical Therapy using Telerehabilitation
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CircaHealth-CircaPain iCT: Targeting circadian rhythmicity using bright light therapy to alleviate chronic low back pain
CircaHealth-CircaPain iCT:利用强光疗法瞄准昼夜节律,缓解慢性腰痛
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Primary care implementation of a no-cost education and exercise program for chronic low back pain (GLA:D Back).
针对慢性腰痛的免费教育和锻炼计划的初级保健实施(GLA:D Back)。
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