MassHEAL - Reducing overdose deaths by 40% (2019-2023)

MassHEAL%20-%20减少%20过量%20死亡%20by%2040%%20(2019-2023)

• 批准号: 10891912
• 负责人: JEFFREY H. SAMET
• 金额: $ 79.98万
• 依托单位: BOSTON MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-15 至 2024-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10891912
• 关键词: Achievement; Acute; Address; Adoption; Age; Attention; Awareness; Black Populations; COVID-19 pandemic; Collaborations; Communities; Comparison arm; Continuity of Patient Care; Data; Data Analyses; Data Sources; Death Rate; Decision Making; Disparity; Equity; Ethnic Origin; Evidence based practice; Frequencies; Gender; Goals; Grant; Health; Health Services Accessibility; Homelessness; Individual; Infrastructure; Infusion procedures; Intervention; Kentucky; Learning; Legal system; Manuscripts; Massachusetts; Measures; Methods; Minority Groups; Naloxone; National Institute of Drug Abuse; Nature; New York; Not Hispanic or Latino; Ohio; Outcome; Outcome Study; Overdose reduction; Parents; Persons; Pharmaceutical Preparations; Policies; Population; Prevention education; Prevention strategy; Process; Protocols documentation; Publications; Race; Randomized; Reach, Effectiveness, Adoption, Implementation, and Maintenance; Reporting; Research Personnel; Resources; Site; Special Population; Surveys; Time; Training; Underserved Population; United States Substance Abuse and Mental Health Services Administration; Waiting Lists; Work; arm; black men; comparison intervention; contextual factors; demographics; design; disparity reduction; ethnic disparity; ethnic minority; ethnic minority population; healing; health equity; implementation strategy; insight; medication for opioid use disorder; meetings; member; minority communities; novel; opioid mortality; opioid overdose; opioid use disorder; overdose death; overdose education; overdose prevention; racial disparity; racial minority; racial minority population; response; satisfaction; sex; shared decision making; social health determinants; social stigma; sociodemographics; treatment as usual; trend

Project Summary/Abstract This supplement aims to explore the impact of the infusion of health equity principles on overdose prevention strategies during implementation of the Communities That Heal (CTH) intervention as part of the HEALing Communities Study (HCS). The HCS is a multi-site, parallel arm, cluster randomized, wait-list controlled trial evaluating the impact of the CTH intervention compared with usual care in wait-list communities, on overdose deaths. The overall goal of the HCS is to reduce opioid overdose deaths by 40% in 67 HCS communities across four states. Communities form coalitions to make shared decisions about what overdose prevention strategies to implement and how best to implement them, particularly strategies that promote Overdose Prevention Education and Naloxone Distribution (OEND) and Medications for Opioid Use Disorder (MOUD). While it is known that minoritized communities (whether due to race, ethnicity, gender, or LGBTQIA+ status) have less and poorer access to treatment for Opioid Use Disorder (OUD) and associated disparities in outcomes, at its outset, HCS did not explicitly aim to reduce disparities or measure the effect of centering equity on overdose prevention. This approach changed in 2020 with acute awareness of the racial and ethnic disparities within the COVID epidemic and the racial awakening in response to the George Floyd killing. This supplement will leverage the existing infrastructure and study stuff of its parent study to analyze survey and other qualitative data already collected. The primary data sources will include surveys of coalition members, completed at four time points during the study period; the Opioid-Overdose Reduction Continuum of Care Approach Tracker (ORCCAT), completed monthly by study staff, that includes overdose prevention information by strategy, sector, venue, population served, coalition approval date, implementation plan developed, date started, number of partners/practices associated with strategy, and mode of delivery; and REACH data, completed by study staff monthly once each strategy is implemented that includes information on number of persons reached and demographics of those reached (e.g., race, ethnicity, sex, age). Data analysis will include both quantitative analysis looking at associations between survey answers regarding health equity topics and incorporation of equity into strategies, as well as qualitative analysis examining how coalitions discussed and prioritized equity topics. This study will be guided by the parent study’s PRISM/RE-AIM(S) conceptual framework with a novel health equity lens to examine how diversifying coalitions and infusing opioid overdose prevention strategies with health equity principles may help reach minoritized communities and how these contextual factors and processes may interact to promote or impede health equity. Results from this study may be used to inform policies, strategies, and practices for incorporating health equity principles when implementing overdose prevention strategies.

项目摘要/摘要 这种补充旨在探讨注入健康公平原则对预防过量的影响 在实施治愈（CTH）干预社区的策略中，作为治愈的一部分 社区研究（HCS）。 HCS是一个多站点，平行的臂，簇随机，等待名单对照试验 与等待名单社区的常规护理相比，评估CTH干预的影响，对过量 死亡人数。 HCS的总体目标是将阿片类药物过量死亡减少40％ 在四个州。社区组成联盟，以对预防过量的预防做出共同的决定 实施策略以及如何最好地实施它们，尤其是促进过量用药的策略 预防教育和纳洛酮分布（OEND）和阿片类药物使用障碍药物（MOUD）。 众所周知，少数社区（无论是由于种族，种族，性别还是LGBTQIA+身份） 获得阿片类药物使用障碍（OUD）的治疗方法较少，相关的差异 从一开始，HCS并没有明确旨在减少分布或衡量居中的效果 预防过量的股权。这种方法在2020年随着种族和种族的急剧意识而发生了变化 乔治·弗洛伊德（George Floyd）杀害乔治·弗洛伊（George Floyd）的差异和种族觉醒内的差异。这 补充剂将利用其父母研究的现有基础设施和研究工作室来分析调查和 其他定性数据已经收集。主要数据源将包括对联盟成员的调查， 在研究期间在四个时间点完成；阿片类药物减少护理连续性 按学习人员每月完成的After Tracker（ORCCAT），其中包括预防信息 按战略，部门，场地，人口服务，联盟批准日期，制定的实施计划，日期 开始，与策略相关的合作伙伴/实践数量以及交付方式；并达到数据， 一旦实施每种策略，包括研究人员每月完成，其中包括有关数量的信息 到达的人以及到达的人口（例如种族，种族，性别，年龄）。数据分析将包括 两种定量分析都介绍有关健康公平主题的调查答案之间的关联和 将公平纳入策略，以及定性分析，以研究联盟如何讨论和 优先的股权主题。这项研究将由父母研究的Prism/re-aim的指导 具有新型健康平等镜头的框架，以检查多样化的联盟和注入阿片类药物过量的多样化 具有健康公平原则的预防策略可能有助于达到少数社区，以及如何 上下文因素和过程可能会互动以促进或阻碍健康公平。这项研究的结果可能 用于告知政策，策略和惯例，以纳入健康公平原则 实施过量预防策略。

项目成果

Applied risk mapping and spatial analysis of address-level decedent data to inform opioid overdose interventions: The Massachusetts HEALing Communities Study.

应用地址级死者数据的风险绘图和空间分析来为阿片类药物过量干预提供信息：马萨诸塞州治愈社区研究。

• DOI: 10.1016/j.drugalcdep.2023.110947
• 发表时间: 2023
• 期刊: Drug and alcohol dependence
• 影响因子: 4.2
• 作者: Pustz,Jennifer;Srinivasan,Sumeeta;Shrestha,Shikhar;Larochelle,MarcR;Walley,AlexanderY;Samet,JeffreyH;Babakhanlou-Chase,Hermik;Carpenter,JaneF;Stopka,ThomasJ
• 通讯作者: Stopka,ThomasJ

Corrigendum to "Model and approach for assessing implementation context and fidelity in the HEALing Communities Study" [Drug Alcohol Depend. 217 (2020) 108330].

• DOI: 10.1016/j.drugalcdep.2021.108742
• 发表时间: 2021-07-01
• 期刊: Drug and alcohol dependence
• 影响因子: 4.2
• 作者: Knudsen HK;Drainoni ML;Gilbert L;Huerta TR;Oser CB;Aldrich AM;Campbell ANC;Crable EL;Garner BR;Glasgow LM;Goddard-Eckrich D;Marks KR;McAlearney AS;Oga EA;Scalise AL;Walker DM
• 通讯作者: Walker DM

Mobile treatment for opioid use disorder: Implementation of community-based, same-day medication access interventions.

阿片类药物使用障碍的移动治疗：实施基于社区的当天药物获取干预措施。

• DOI: 10.1016/j.josat.2023.209272
• 发表时间: 2024
• 期刊: Journal of substance use and addiction treatment
• 作者: Chatterjee,Avik;Baker,Trevor;Rudorf,Maria;Walt,Galya;Stotz,Caroline;Martin,Anna;Kinnard,ElizabethN;McAlearney,AnnScheck;Bosak,Julie;Medley,Bethany;Pinkhover,Allyson;Taylor,JessicaL;Samet,JeffreyH;Lunze,Karsten
• 通讯作者: Lunze,Karsten

Intranasal Naloxone for Opioid Overdose.

鼻内纳洛酮治疗阿片类药物过量。

• DOI: 10.1001/jama.2023.23248
• 发表时间: 2024
• 期刊: JAMA
• 作者: Taylor,JessicaL;Lasser,KarenE
• 通讯作者: Lasser,KarenE