Elucidating the chemical biology of the druggable targets in enteric pathogens C. jejuni & E. coli
Elucidating the chemical biology of the druggable targets in enteric pathogens C. jejuni & E. coli
批准号:
10892592
负责人:
M. Ashfaqul Alam
金额:
$23.54万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2023
资助国家:
美国
项目状态:
未结题
起止时间:
2023-02-01 至 2025-01-31
中文摘要
本提案的目的是阐明微生物代谢物和小分子的化学生物学
专门针对导致肠道感染和炎症的肠道病原体。其成果将
促进制定干预战略,以具体控制
在不改变整个肠道微生物群的情况下,
英文摘要
This proposal’s objective is to elucidate the chemical biology of microbial metabolites and small molecules
to specifically target intestinal pathogens, which cause intestinal infection & inflammation. The findings will
facilitate the development of intervention strategies to specifically control the emergence and spread of
antibiotic resistance in this significant human pathogen without altering the entire gut microbiota.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Impact of dysbiotic and symbiotic catabolism of luminal amino acids on intestinal epithelial barrier function and inflammation
-
批准号:10912096
-
项目类别:
-
资助金额:$37.51万
-
财政年份:2023
-
负责人:M. Ashfaqul Alam
-
依托单位:
Microbially generated protons mediate interkingdom host-microbiome cross-talk and maintain intestinal homeostasis via reciprocal functions of two proton-sensing GPCRs
-
批准号:10444190
-
项目类别:
-
资助金额:$8.42万
-
财政年份:2017
-
负责人:M. Ashfaqul Alam
-
依托单位:
Microbially generated protons mediate interkingdom host-microbiome cross-talk and maintain intestinal homeostasis via reciprocal functions of two proton-sensing GPCRs
-
批准号:9371648
-
项目类别:
-
资助金额:$10.74万
-
财政年份:2017
-
负责人:M. Ashfaqul Alam
-
依托单位:
Microbially generated protons mediate interkingdom host-microbiome cross-talk and maintain intestinal homeostasis via reciprocal functions of two proton-sensing GPCRs
-
批准号:9751845
-
项目类别:
-
资助金额:$4.26万
-
财政年份:2017
-
负责人:M. Ashfaqul Alam
-
依托单位:
Microbially generated protons mediate interkingdom host-microbiome cross-talk and maintain intestinal homeostasis via reciprocal functions of two proton-sensing GPCRs
-
批准号:10136335
-
项目类别:
-
资助金额:$6.32万
-
财政年份:2017
-
负责人:M. Ashfaqul Alam
-
依托单位:
国内基金
海外基金
Journal of Integrative Plant Biology
-
批准号:31024801
-
项目类别:专项基金项目
-
资助金额:24.0万元
-
批准年份:2010
-
负责人:贺萍
-
依托单位: