Elucidating the chemical biology of the druggable targets in enteric pathogens C. jejuni & E. coli
Elucidating the chemical biology of the druggable targets in enteric pathogens C. jejuni & E. coli
批准号:
10892592
负责人:
M. Ashfaqul Alam
金额:
$23.54万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2023
资助国家:
美国
项目状态:
未结题
起止时间:
2023-02-01 至 2025-01-31
中文摘要
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英文摘要
This proposal’s objective is to elucidate the chemical biology of microbial metabolites and small molecules
to specifically target intestinal pathogens, which cause intestinal infection & inflammation. The findings will
facilitate the development of intervention strategies to specifically control the emergence and spread of
antibiotic resistance in this significant human pathogen without altering the entire gut microbiota.
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会议论文
Impact of dysbiotic and symbiotic catabolism of luminal amino acids on intestinal epithelial barrier function and inflammation
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批准号:10912096
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项目类别:
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资助金额:$37.51万
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财政年份:2023
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负责人:M. Ashfaqul Alam
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依托单位:
Microbially generated protons mediate interkingdom host-microbiome cross-talk and maintain intestinal homeostasis via reciprocal functions of two proton-sensing GPCRs
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批准号:10444190
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项目类别:
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资助金额:$8.42万
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财政年份:2017
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负责人:M. Ashfaqul Alam
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依托单位:
Microbially generated protons mediate interkingdom host-microbiome cross-talk and maintain intestinal homeostasis via reciprocal functions of two proton-sensing GPCRs
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批准号:9371648
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项目类别:
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资助金额:$10.74万
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财政年份:2017
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负责人:M. Ashfaqul Alam
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依托单位:
Microbially generated protons mediate interkingdom host-microbiome cross-talk and maintain intestinal homeostasis via reciprocal functions of two proton-sensing GPCRs
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批准号:9751845
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项目类别:
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资助金额:$4.26万
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财政年份:2017
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负责人:M. Ashfaqul Alam
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依托单位:
Microbially generated protons mediate interkingdom host-microbiome cross-talk and maintain intestinal homeostasis via reciprocal functions of two proton-sensing GPCRs
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批准号:10136335
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项目类别:
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资助金额:$6.32万
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财政年份:2017
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负责人:M. Ashfaqul Alam
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依托单位:
国内基金
海外基金
Journal of Integrative Plant Biology
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批准号:31024801
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项目类别:专项基金项目
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资助金额:24.0万元
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批准年份:2010
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负责人:贺萍
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依托单位: