Es Tiempo/It’s Time: A Multi-Channel Multi-Cultural Communication Campaign for Improvements in Education and Outcomes on Human Papilloma Virus Vaccinations and HPV Related Cancers in Vulnerable popula

摘要 虽然人类乳头瘤病毒（HPV）疫苗取得了很大进展，但仍有一些社区 HPV疫苗接种率滞后。原因各不相同。HPV疫苗接种率最低， 西班牙裔/拉丁美洲人/拉丁美洲人（H/L），非美国出生父母的亚洲青少年男孩和H/L青少年女孩，以及 生活在美国的非洲移民父母的青少年，其中包括来自拉丁美洲的土著群体 （美洲印第安人）和非洲（埃塞俄比亚人，埃塞俄比亚人，塞内加尔人）在洛杉矶。洛杉矶的数据显示，五分之一的父母 来自H/L、非洲血统和华裔美国人家庭（n = 357）的HPV疫苗高耐药性和超过50% 担心安全性和副作用研究表明 对HPV相关因素、疫苗的健康素养低 误解是造成这些群体疫苗接种率低的重要因素。 此外，虽然HPV 没有性别特异性，HPV的女性化，重点是宫颈癌，受到其性别的影响， 这反过来又影响了HPV相关信息的接受及其应用 在男孩和男子中，特别缺乏关于其他HPV相关癌症的信息， 量身定做、适合年龄的语言材料，适合移民群体。USC Norris Comprehensive附近酒店 癌症中心（南加州大学NCCC）建议在轨道1（青年和青少年）工作，以开发和测试一个 开展宣传活动，提供针对不同文化和年龄的关于HPV相关癌症的教育材料， 促进在男性和女性青少年/年轻人（10- 30岁）中开始接种HPV疫苗， HL，中国和非洲裔美国人/非洲裔移民社区。我们将与社区合作 合作伙伴巴里奥行动青年中心，庆祝生活黑人教会部，视觉和妥协，和7个当地 Oscar Romero先生诊所的一部分，唐人街服务中心（CSC），以及Vision y Compromiso（promotores de salud）.利用南加州大学NCCC癌症中心COE资源， 从我们以前的行政补充调查结果（Tsui/Baezconde-Garbanati），我们将扩大我们的范围， 男性和女性弱势青少年/年轻人（AYA）在不同的观众。定量（预 和运动后）以及来自倾听会议和焦点小组的定性数据将支持制定 运动要素及其评价。文化专家和适龄专家（包括青少年）， 社区咨询委员会和合作伙伴将支持运动的发展。我们将使用人工 智能（AI）技术/平台，以制作适合年龄和文化的教育材料， 语言接种疫苗的证明将通过医疗记录审查和我们的CIMHC诊所的报告， 同意的参与者。社区合作伙伴将帮助确定、培训和建立社区劳动力队伍 由社区卫生教育工作者和宣传员组成。

Abstract Although much progress has been made with the Human Papilloma Virus (HPV) vaccine, still some communities lag in HPV vaccination rates. Reasons for this vary. HPV vaccination is lowest among Hispanic/Latinos/Latinas(H/L), Asian adolescent boys and H/L adolescent girls of non-US-born parents and for adolescents of African immigrant parents living in the U.S. These include indigenous groups from Latin America (Amerindians) and Africa (Ethiopians, Nigerians, Senegalese) In Los Angeles. LA data show one-fifth of parents from H/L, African ancestry, and Chinese American families (n = 357) high HPV vaccine resistance and over 50% worried about safety or side effects. Research shows low health literacy on HPV related factors, vaccine misconceptions are important factors contributing to low vaccine uptake in these groups. Further, though HPV is not gender-specific, the feminization of HPV with a focus on cervical cancer has been impacted by its sexual transmissibility; and this in turn has influenced the acceptance of HPV related information and its application among boys and men, especially lacking has been information on other HPV related cancers and culturally tailored, age appropriate and in language materials for immigrant origin groups. The USC Norris Comprehensive Cancer Center (USC NCCC) proposes to work on Track 1 (youth and adolescents) to develop and test a communication campaign with culturally and age-tailored educational materials on HPV related cancers and promote initiation of the HPV Vaccine among both male and female adolescent/young adults (10-30ys) in the HL, Chinese and African American/African-origin immigrant communities. We will collaborate with community partners Barrio Action Youth Center, Celebrate Life Black Churches Ministry, Vision y Compromiso, and 7 local FQHC clinics part of Clinicas Monsenor Oscar Romero, and the Chinatown Service Center (CSC), and Vision y Compromiso (promotores de salud). Leveraging USC NCCC Cancer Center COE resources and informed by findings from our previous administrative supplement (Tsui/Baezconde-Garbanati) we will extend our reach to both male and female vulnerable adolescents/young adults (AYA) in diverse audiences. Both quantitative (pre and post campaign) and qualitative data from listening sessions and focus groups will support development of campaign elements and its evaluation. Cultural experts and age-appropriate experts (including adolescents), our Community Advisory Committee and partners will support campaign development. We will use Artificial Intelligence (AI) technology/platforms to produce age and culturally appropriate educational materials in language. Proof of vaccinations will be via medical records review and reports by our FQHC clinics regarding consented participants. Community partners will help identify, train, and establish a community workforce composed of community health educators and promotores de salud for dissemination.