Prophylactic Mastectomy: The Patient Experience

预防性乳房切除术：患者体验

• 批准号: 6702861
• 负责人: ANDREA F PATENAUDE
• 金额: $ 8.55万
• 依托单位: DANA-FARBER CANCER INST
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-12 至 2005-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6702861
• 关键词: age difference; behavioral /social science research tag; body image; breast neoplasms; breast surgery; cancer prevention; case history; clinical research; communication; decision making; emotions; family genetics; family structure /dynamics; female; human data; human therapy evaluation; interpersonal relations; interview; mental health; monograph; outcomes research; plastic surgery; self concept; sex behavior; sex partner

DESCRIPTION (provided by applicant): Prophylactic mastectomy (PM) has been shown to reduce the risk of breast cancer 90% in women at high and moderate risk, but its use is limited by low acceptability. Researchers caution that this is a highly personal decision, but patients and providers have little data about psychosocial outcomes of PM. Project goals are: a. To describe the self-perceived benefits of PM and the physical, emotional, and interpersonal impacts; b. To describe the impact of cancer family history and family communication on decision-making for and outcomes of PM; c. To utilize case comparisons to assess the relative influence of medical, psychological, and family factors in determining positive or adverse outcomes of PM; and, d. To produce a monograph based on the qualitative analysis and emphasizing first-person narratives for use by women considering PM and as a tool for health care providers in advising their patients. This project will qualitatively analyze 108 interview narratives from a previously-funded research project on psychological consultation needs of women considering or recovering from PM. The sample includes women with cancer who underwent unilateral PM (n=50), unaffected women who chose bilateral PM (n=21), and women considering PM (n=37). Analysis will utilize issue-oriented and cross-case research methods. Modal and exceptional cases will be developed. A monograph utilizing the narratives and organizing them into user-friendly topic areas for patients will be developed. Reports for providers will also hopefully enhance advice to patients. Future research may assess utility of this material for women considering PM and for health care providers. Data from the project will inform hypothesis formation for future studies of PM.

描述（由申请人提供）：预防性乳房切除术（PM）已被证明可将高风险和中度风险女性患乳腺癌的风险降低90%，但其使用受到低可接受性的限制。研究人员警告说，这是一个高度个人的决定，但患者和提供者几乎没有关于PM心理社会结果的数据。项目目标是：a.描述项目管理的自我感知利益，以及对身体、情感和人际关系的影响；b.描述癌症家族史和家庭沟通对PM决策和结果的影响；c.利用病例比较来评估医学、心理和家庭因素在确定PM阳性或不良结局方面的相对影响；d.在定性分析的基础上编写专著，强调第一人称叙述，以供考虑PM的妇女使用，并作为卫生保健提供者向患者提供建议的工具。本项目将定性分析108个访谈叙述从先前资助的研究项目中考虑或从PM中恢复的女性的心理咨询需求。样本包括接受单侧PM的癌症女性（n=50），选择双侧PM的未受影响女性（n=21）和考虑PM的女性（n=37）。分析将采用面向问题和跨案例的研究方法。将开发模态和例外情况。一个专著利用叙事和组织他们到用户友好的主题领域为患者将开发。医疗服务提供者的报告也有望加强对患者的建议。未来的研究可能会评估该材料对考虑PM的妇女和卫生保健提供者的效用。该项目的数据将为未来PM研究的假设形成提供信息。