Psychosocial and Ethical Literature in Cancer Genetics

癌症遗传学的心理社会和伦理文献

• 批准号: 6474206
• 负责人: ANDREA F PATENAUDE
• 金额: $ 8.29万
• 依托单位: DANA-FARBER CANCER INST
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-09-30 至 2004-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6474206
• 关键词: Psychosocial; Ethical; Literature; Cancer; Genetics

This application proposes the preparation of a definitive book on state-of-theart psychosocial research and ethical writing and policy relating to cancer genetics and genetic testing for cancer genes. One decade after the initiation of the Ethical, Legal, and Social Implications Program of the Human Genome and the start of the modern era in cancer genetics, this book will summarize and critique existing social science and medical literature to try to answer important questions about the human impact of genetic technology. Advances in genetics promise to catalyze a fundamental change in the practice of medicine. Genetic advances have led to new approaches to the assessment of cancer risk. The coming decades will see an explosion of information about the hereditary nature of disease susceptibility. From its inception, the Human Genome Project has recognized the enormous social ramifications of decoding the human genome. Early indications are strong that psychosocial factors play a major role in attitudes towards and utilization of genetic technology. Social science research can provide data on which to base development of interventions to maximize the benefits of genetic research. It is crucial, however, that such interventions consider also the ethical aspects of human use of genetic technology. The goals of this project are 1. ) To summarize and critique the literature from a broad spectrum of social science and genetic disciplines related to psychosocial and ethical aspects of cancer genetic testing, 2.) To make the area of psychosocial and ethical aspects of cancer genetics more approachable to new/young social science investigators, 3.) To create links and encourage future collaborative research between social scientists working in genetic testing and social scientists with specialties in relevant related areas, 4.) To encourage awareness of the work of international social scientists with regard to psychosocial aspects of cancer genetic testing, and 5.) To encourage translational integration of psychosocial research findings into the development of cancer genetics programs through the provision of accessible summaries of psychosocial and ethical literature for use by medical and genetic professionals who are establishing cancer genetics programs.

本申请建议编写一本关于癌症遗传学和癌症基因遗传检测的最新社会心理研究和伦理写作和政策的权威书籍。在人类基因组的伦理、法律的和社会影响计划启动十年后，以及癌症遗传学现代时代的开始，本书将总结和批判现有的社会科学和医学文献，试图回答有关遗传技术对人类影响的重要问题。遗传学的进步有望催化医学实践的根本变革。遗传学的进步带来了评估癌症风险的新方法。在未来的几十年里，关于疾病易感性的遗传本质的信息将爆炸式增长。从一开始，人类基因组计划就认识到解码人类基因组的巨大社会影响。早期迹象表明，心理社会因素在对待和利用遗传技术的态度方面起着重要作用。社会科学研究可以提供数据， 以制定干预措施为基础，最大限度地发挥遗传研究的效益。然而，至关重要的是，这种干预措施还应考虑到人类使用遗传技术的伦理方面。该项目的目标是1。总结和评论与癌症基因检测的社会心理和伦理方面有关的广泛的社会科学和遗传学科的文献，2。使社会心理和伦理领域 癌症遗传学方面更容易接近新的/年轻的社会科学研究人员，3。建立联系，鼓励从事基因检测的社会科学家和在相关领域有专长的社会科学家之间未来的合作研究，4。鼓励了解国际社会科学家在癌症基因检测的心理社会方面的工作，以及5。通过提供以下服务，鼓励将社会心理学研究成果转化为癌症遗传学项目的发展 可访问的社会心理和伦理文献摘要，供正在建立癌症遗传学项目的医学和遗传学专业人员使用。