Prophylactic Mastectomy: The Patient Experience

预防性乳房切除术：患者体验

• 批准号: 6800007
• 负责人: ANDREA F PATENAUDE
• 金额: $ 8.55万
• 依托单位: DANA-FARBER CANCER INST
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-12 至 2006-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6800007
• 关键词: age difference; behavioral /social science research tag; body image; breast neoplasms; breast surgery; cancer prevention; case history; clinical research; communication; decision making; emotions; family genetics; family structure /dynamics; female; human data; human therapy evaluation; interpersonal relations; interview; mental health; monograph; outcomes research; plastic surgery; self concept; sex behavior; sex partner

DESCRIPTION (provided by applicant): Prophylactic mastectomy (PM) has been shown to reduce the risk of breast cancer 90% in women at high and moderate risk, but its use is limited by low acceptability. Researchers caution that this is a highly personal decision, but patients and providers have little data about psychosocial outcomes of PM. Project goals are: a. To describe the self-perceived benefits of PM and the physical, emotional, and interpersonal impacts; b. To describe the impact of cancer family history and family communication on decision-making for and outcomes of PM; c. To utilize case comparisons to assess the relative influence of medical, psychological, and family factors in determining positive or adverse outcomes of PM; and, d. To produce a monograph based on the qualitative analysis and emphasizing first-person narratives for use by women considering PM and as a tool for health care providers in advising their patients. This project will qualitatively analyze 108 interview narratives from a previously-funded research project on psychological consultation needs of women considering or recovering from PM. The sample includes women with cancer who underwent unilateral PM (n=50), unaffected women who chose bilateral PM (n=21), and women considering PM (n=37). Analysis will utilize issue-oriented and cross-case research methods. Modal and exceptional cases will be developed. A monograph utilizing the narratives and organizing them into user-friendly topic areas for patients will be developed. Reports for providers will also hopefully enhance advice to patients. Future research may assess utility of this material for women considering PM and for health care providers. Data from the project will inform hypothesis formation for future studies of PM.

描述（由申请人提供）：预防性乳房切除术（PM）已被证明可将高风险和中度风险女性的乳腺癌风险降低90%，但其使用受到可接受性低的限制。研究人员警告说，这是一个高度个人化的决定，但患者和提供者几乎没有关于PM的心理社会后果的数据。项目目标是：a。描述自我感知的PM的好处和身体，情感和人际关系的影响; B。描述癌症家族史和家庭沟通对PM决策和结果的影响; c.利用病例比较来评估医学、心理和家庭因素在确定PM的积极或不良结局中的相对影响;以定性分析为基础编写一本专著，强调第一人称叙述，供考虑PM的妇女使用，并作为卫生保健提供者向患者提供咨询的工具。本研究将从一个先前资助的研究项目中定性分析108个关于考虑或从PM中恢复的妇女的心理咨询需求的访谈叙述。样本包括接受单侧PM的癌症女性（n=50），选择双侧PM的未受影响的女性（n=21）和考虑PM的女性（n=37）。分析将采用面向问题和跨案例的研究方法。将开发模式和例外情况。将开发一个利用叙述并将其组织成用户友好的患者主题领域的专著。提供者的报告也有望加强对患者的建议。未来的研究可能会评估这种材料的实用性考虑PM的妇女和卫生保健提供者。该项目的数据将为未来的PM研究提供假设。

项目成果

Support needs and acceptability of psychological and peer consultation: attitudes of 108 women who had undergone or were considering prophylactic mastectomy.

支持需求和心理和同伴咨询的可接受性：108名经历或正在考虑预防性乳房切除术的妇女的态度。

• DOI: 10.1002/pon.1279
• 发表时间: 2008-08
• 期刊: PSYCHO-ONCOLOGY
• 影响因子: 3.6
• 作者: Patenaude, Andrea F.;Orozco, Sara;Li, Xiaochun;Kaelin, Carolyn M.;Gadd, Michelle;Matory, Yvedt;Mayzel, Kathleen;Roche, Constance A.;Smith, Barbara L.;Farkas, Walden;Garber, Judy F.
• 通讯作者: Garber, Judy F.