Brief Intervention for Smokers: Cue Reactivity & Smoking

对吸烟者的简短干预：提示反应

• 批准号: 6767184
• 负责人: DAVID J DROBES
• 金额: $ 16.08万
• 依托单位: H. LEE MOFFITT CANCER CTR & RES INST
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-05-15 至 2006-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6767184
• 关键词: behavior modification; behavioral /social science research tag; clinical research; cognitive behavior therapy; computer program /software; cues; human subject; motivation; nutrition; nutrition related tag; patient oriented research; smoking cessation; tobacco abuse; tobacco abuse education

DESCRIPTION (provided by applicant): Smoking remains among the major preventable causes of death in our society. Despite the recent proliferation of pharmaceutical and behavioral methods for smoking cessation, approximately one out of every four adults continues to smoke. Unfortunately, the majority of smokers appear to have low motivation for quitting at any given time. Although current guidelines from the U.S. Public Health Service recommend that brief interventions be provided to all smokers who are not currently motivated to quit, the effectiveness of brief interventions have not been well established, and research has not elucidated mechanisms whereby brief interventions may exert change in smoking behavior. The primary aim of this Stage Ia exploratory/developmental (R21) research is to examine specific cognitive/affective mediators of smoking behavior following a brief 'priming' intervention delivered to low-motivated smokers. Phase I will refine a brief computer-tailored 'Smoking-Related Priming' (SRP) intervention by incorporating feedback from a group (n=20) of low-motivated smokers. Phase II will comprise a clinical laboratory study (n=105) to evaluate the theoretically-derived prediction that SRP will increase negative affect (e.g., approach-avoidance conflict, cognitive dissonance) and arousal elicited by smoking cues, and that these cognitive/affective reactions will mediate effects of the intervention on acute smoking behavior. In this study, SRP will be compared with 'Nutrition-Related Priming' and 'No Priming' conditions. A secondary aim is to determine if physiological arousal during specific components of SRP is related to smoking behavior following the intervention. Overall, this project will lay the groundwork for future exploratory research (Stage Ib) that will continue to evaluate relationships between brief intervention for low-motivated smokers and relevant smoking outcomes. Ultimately, the information obtained via this program of research will be used to maximize the efficacy of brief interventions (Stage II) that can be widely disseminated to low-motivated smokers in community settings (Stage III).

描述（由申请人提供）： 吸烟仍然是我们社会中可预防的主要死亡原因之一。尽管最近用于戒烟的药物和行为方法不断涌现，但大约四分之一的成年人仍在吸烟。不幸的是，大多数吸烟者似乎在任何特定时间都没有戒烟动机。尽管美国公共卫生服务部目前的指南建议向所有目前没有戒烟动机的吸烟者提供简短的干预措施，但短期干预措施的有效性尚未得到充分证实，并且研究尚未阐明短期干预措施可能改变吸烟行为的机制。这项 Ia 阶段探索性/发展性 (R21) 研究的主要目的是在对低积极性吸烟者进行简短的“启动”干预后，检查吸烟行为的特定认知/情感调节因素。第一阶段将通过纳入一组（n = 20）低积极性吸烟者的反馈来完善简短的计算机定制的“吸烟相关启动”（SRP）干预措施。第二阶段将包括一项临床实验室研究（n = 105），以评估理论上得出的预测，即SRP将增加吸烟线索引起的负面情绪（例如，接近-回避冲突、认知失调）和唤醒，并且这些认知/情感反应将介导干预对急性吸烟行为的影响。在这项研究中，SRP 将与“营养相关启动”和“无启动”条件进行比较。第二个目的是确定 SRP 特定组成部分期间的生理唤醒是否与干预后的吸烟行为有关。总体而言，该项目将为未来的探索性研究（第一阶段）奠定基础，该研究将继续评估对低动机吸烟者的短暂干预与相关吸烟结果之间的关系。最终，通过该研究计划获得的信息将用于最大限度地提高简短干预措施（第二阶段）的功效，这些干预措施可以广泛传播给社区环境中的低积极性吸烟者（第三阶段）。