Using 3D printing technology to develop architecturally-controlled synthetic bone substitutes

利用3D打印技术开发结构控制的合成骨替代品

• 批准号: LP140100900
• 负责人: Prof Hala Zreiqat
• 金额: $ 28.44万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Projects
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 2020-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LP140100900
• 关键词: Using; 3D; printing; technology; develop

With the ageing population, there is increasing demand for synthetic materials that can regenerate bone. However, purely synthetic bone-substitute biomaterials cannot regenerate large bone defects in weight-bearing conditions due to their fragility. This project aims to develop a customisable, biodegradable, biocompatible and mechanically strong and tough scaffold that overcomes this long-standing problem. The project aims to achieve this by applying an innovative combination of cutting-edge 3D printing technology, advanced computational modelling and design techniques to produce a next-generation bioceramic scaffold with optimised architecture. This approach aims also to enable the possibility of producing custom-made implants for individual requirements.

随着人口老龄化，对可以再生骨骼的合成材料的需求越来越大。然而，纯合成的骨替代生物材料由于其脆弱性而不能在承重条件下再生大的骨缺损。该项目旨在开发一种可定制的，可生物降解的，生物相容的，机械强度和坚韧的支架，以克服这个长期存在的问题。该项目旨在通过应用先进的3D打印技术，先进的计算建模和设计技术的创新组合来实现这一目标，以生产具有优化结构的下一代生物陶瓷支架。这种方法的目的还在于使生产个性化需求的定制植入物成为可能。