Using 3D printing technology to develop architecturally-controlled synthetic bone substitutes

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With the ageing population, there is increasing demand for synthetic materials that can regenerate bone. However, purely synthetic bone-substitute biomaterials cannot regenerate large bone defects in weight-bearing conditions due to their fragility. This project aims to develop a customisable, biodegradable, biocompatible and mechanically strong and tough scaffold that overcomes this long-standing problem. The project aims to achieve this by applying an innovative combination of cutting-edge 3D printing technology, advanced computational modelling and design techniques to produce a next-generation bioceramic scaffold with optimised architecture. This approach aims also to enable the possibility of producing custom-made implants for individual requirements.