X-Ray Nano-CT Systems for Orthopedic Implant Coatings

描述（由申请人提供）： 我们建议开发一种专门设计用于骨科植入物涂层的无损3D成像的X射线显微断层扫描系统，以研究骨折力学，从而提高植入物技术。所提出的X射线显微断层扫描系统提供了独特的优势，在骨折力学的研究和先进的涂层材料的开发骨科植入物的无损三维成像的可见光和电子显微镜为基础的方法。具体来说，它将允许在未受干扰的状态下原位研究80 nm分辨率的地下裂纹，而不需要切割样品以冒改变裂纹的风险。它还允许在任何材料中或通过任何材料看到裂缝，而不管光学透明度如何（例如模拟体液），并且将使同一裂缝能够重复成像以监测其进展。硬X射线显微镜将有更广泛的用途，用于其他类型的植入物涂层，如商业羟基磷灰石的断裂力学研究，以及任何固体材料内部结构的无损成像。

DESCRIPTION (provided by applicant): We propose to develop an x-ray microtomography system specifically designed for nondestructive 3D imaging of orthopedic implant coatings to investigate fracture mechanics for the purpose of improving the implant technology. The proposed x-ray microtomography system offers unique advantages over visible-light and electron microscope based methods for nondestructive 3D imaging of orthopedic implants in the study of fracture mechanics and development of advanced coating materials. Specifically it would allow 80nm-resolution studies of subsurface cracks in situ in an unperturbed state without the need of cutting the sample to risk altering the crack. It would also allow the cracks to be seen in or through any material regardless of optical transparency (such as simulated body fluid) and would enable the same crack to be imaged repeatedly to monitor its progress. The hard x-ray microscope will have much wider usage for fracture mechanics studies of other types of implant coatings, such as commercial hydroxyapatite, and nondestructive imaging of internal structures in any solid materials.