Multiethnic Pediatric Eye Disease Study (MEPEDS)

多民族小儿眼病研究 (MEPEDS)

• 批准号: 6736253
• 负责人: ROHIT VARMA
• 金额: $ 245.83万
• 依托单位: UNIVERSITY OF SOUTHERN CALIFORNIA
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-30 至 2007-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6736253
• 关键词: African American; Hispanic Americans; amblyopia; caucasian American; clinical research; cooperative study; data collection methodology /evaluation; disease /disorder proneness /risk; epidemiology; eye coordination disorder; eye disorder; eye disorder diagnosis; eye refraction disorder; eye refractometry; functional ability; health care service availability; health care service utilization; human subject; infant human (0-1 year); interview; preschool child (1-5); questionnaires; racial /ethnic difference; retinography; vision disorders; vision tests

DESCRIPTION (provided by applicant): Vision disorders such as strabismus, amblyopia and refractive error are the leading causes of handicapping conditions in childhood. Over the past decade, there is an increasing amount of evidence that suggest that early diagnosis and treatment of these ocular disorders can result in beneficial outcomes. Indeed, early detection and treatment is critical because it can decrease the burden of visual impairment on the child, her/his family and the society at large. This has lead to widespread interest in screening programs. However, despite the wealth of knowledge regarding early treatment, very little evidence exists on the prevalence of vision disorders in children. Additionally, almost no evidence exists on minority populations. The primary objective of this study, the Multi-Ethnic Pediatric Eye Disease Study (MEPEDS) is to improve our understanding of the magnitude and causes of ocular disease problems in population based samples of African-American, Latino and Non-Hispanic White children in the United States. A population-based sample of three thousand children from each of the three ethnic/racial groups will undergo a comprehensive eye examination to determine the prevalence of refractive error, strabismus and amblyopia. MEPEDS will also be studying selected demographic, biological and behavioral risk factors associated with these diseases and the consequences of these diseases from a health related quality of life perspective.

描述（由申请人提供）：视力障碍，例如斜视，弱视和屈光不正是童年残障条件的主要原因。在过去的十年中，越来越多的证据表明，这些眼部疾病的早期诊断和治疗可能会导致有益的结果。确实，早期发现和治疗至关重要，因为它可以减轻儿童，他/他的家人和整个社会的视觉障碍负担。这引起了人们对筛查计划的普遍兴趣。但是，尽管关于早期治疗的知识丰富，但几乎没有证据表明儿童视力障碍的流行。此外，几乎没有证据表明少数群体。这项研究的主要目的是，多种族的小儿眼病研究（MEPEDS）是为了提高我们对美国非裔美国人，拉丁裔和非西班牙裔白人儿童基于人群的类样品的大小和原因的理解。来自三个族裔/种族群体中每个儿童的三千名儿童的基于人群的样本将进行全面的眼科检查，以确定屈光不正，斜视和弱视的流行率。 MEPEDS还将研究与这些疾病相关的人口，生物学和行为危险因素以及这些疾病的后果，从与健康相关的生活质量的角度来看。