Training in the Pharmacological Sciences

药理学培训

• 批准号: 10715195
• 负责人: Michelle L Bland
• 金额: $ 26.53万
• 依托单位: UNIVERSITY OF VIRGINIA
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-07-01 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10715195
• 关键词: Science; Training; pharmacologic

The mission of UVA’s predoctoral Pharmacological Sciences Training Program (PSTP) is to foster scientific inquiry using pharmacologic strategies to address important biomedical questions. With this application, we request funds to support 7 predoctoral trainees, who will be appointed to the training grant during their second and third years of study. The PSTP curriculum includes rigorous didactic instruction and three research rotations during the first year with selection of a thesis advisor in February of that year. During the second year, students develop an independent research project and take a written and oral advancement to candidacy examination. The following three years consist largely of a research project focusing on collaboration and publication culminating in a written dissertation and seminar. Integral to the PSTP are activities that enable trainees to: a) understand responsible conduct of research (RCR) and laboratory safety, b) develop skills in rigor & reproducibility, c) receive and give feedback during evaluation, d) develop career interests, including use of Individual Development Plans, e) improve written and oral communication skills, and f) learn critical analysis via journal clubs and seminars. Research in the PSTP is inter-disciplinary and includes intermediary metabolism, neuroscience, infectious disease, immunology, membrane biophysics, drug discovery and design, and proteomics. The PSTP is based in the Department of Pharmacology and nearly all trainees are Pharmacology PhD students with an occasional Neuroscience program PhD student. The PSTP preceptors are 25 faculty drawn from 8 different academic departments across UVA’s research enterprise. These faculty are evaluated by the PSTP Steering Committee for research excellence, mentoring skills, and commitment to diversity. Faculty are required to compete mentor training before accepting a PSTP trainee. Oversight of the PSTP program is achieved by the Steering Committee aided by an expert Internal Advisory Committee. The PSTP builds on 45+ years of educational excellence in the Pharmacological Sciences that has no equivalent elsewhere at UVA. Historically, the PSTP mentors have included 2 Nobel laureates. Approximately 8 students are enrolled annually from a pool of ~200 applicants after a rigorous, holistic application process culminating with in-person interviews. Matriculants from under-represented minority (URM) groups now represent ~20% of the total, with an overall F:M ratio of ~2:1. The URM candidates, those from disadvantaged backgrounds and students with disabilities are actively sought in outreach programs such as a highly successful undergraduate Summer Research Training Program (SRIP). UVA PSTP graduates are highly sought-after in academia, industry, and public service due to their excellence as research scientists.

UVA 博士前药理学科学培训计划 (PSTP) 的使命是培养科学 使用药理学策略来解决重要的生物医学问题的探究。通过这个应用程序，我们 请求资金支持 7 名博士前培训生，他们将在第二次培训期间获得培训补助金 和第三年的学习。 PSTP 课程包括严格的教学指导和三项研究 第一年进行轮换，并于当年二月选择论文导师。第二次期间 这一年，学生开发一个独立的研究项目，并通过书面和口头的方式获得候选资格 考试。接下来的三年主要包括一个专注于合作和 出版物最终形成书面论文和研讨会。 PSTP 不可或缺的活动是： 学员：a) 了解负责任的研究行为 (RCR) 和实验室安全，b) 培养以下方面的技能： 严谨性和可重复性，c) 在评估过程中接收并提供反馈，d) 发展职业兴趣，包括 使用个人发展计划，e) 提高书面和口头沟通技巧，以及 f) 学习关键知识 通过期刊俱乐部和研讨会进行分析。 PSTP 的研究是跨学科的，包括中介 新陈代谢、神经科学、传染病、免疫学、膜生物物理学、药物发现和设计、 和蛋白质组学。 PSTP 设在药理学系，几乎所有学员都是 药理学博士生，偶尔还有神经科学项目博士生。 PSTP 导师 由来自 UVA 研究机构 8 个不同学术部门的 25 名教员组成。这些师资 由 PSTP 指导委员会评估卓越的研究、指导技能和对 多样性。教师在接受 PSTP 实习生之前必须参加导师培训。监督 PSTP 计划由指导委员会在专家内部咨询委员会的协助下完成。这 PSTP 建立在药理学科学领域 45 多年的卓越教育基础上，无与伦比 UVA的其他地方。历史上，PSTP 导师中曾有 2 位诺贝尔奖获得者。约8名学生 经过严格、全面的申请流程后，每年从约 200 名申请者中脱颖而出 面对面采访。来自代表性不足的少数族裔 (URM) 群体的预科生现在占 20% 左右 总数，总体 F:M 比率约为 2:1。 URM 候选人、来自弱势背景的候选人以及 在外展计划中积极寻找残疾学生，例如非常成功的本科生 夏季研究培训计划（SRIP）。 UVA PSTP 毕业生在学术界备受追捧， 由于他们作为研究科学家的卓越表现，他们在工业和公共服务领域取得了巨大成就。