Genetic and Developmental Mechanisms of Pediatric Diseases

儿科疾病的遗传与发育机制

• 批准号: 7157598
• 负责人: Edward Bowersox Clark
• 金额: $ 43.2万
• 依托单位: UNIVERSITY OF UTAH
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-04-11 至 2007-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7157598
• 关键词: Anatomy; Biology; Biometry; Childhood; Congenital Abnormality; Databases; Development; Discipline; Disease; Education; Educational Background; Ethical Issues; Faculty; Funding; Human; Human Genetics; Inherited; Institutes; Malignant Neoplasms; Medical; Medical Genetics; Mentors; Molecular Biology; Neurobiology; Pathology; Pediatrics; Physicians; Population Database; Records; Research; Research Design; Research Personnel; Research Support; Resources; Scientist; Training Programs; Universities; Utah; Writing; base; career; developmental genetics; human disease; multidisciplinary; pediatric department; programs

DESCRIPTION (provided by applicant): This application describes the CHRCDA program of the University of Utah. This program focuses broadly on the genetic and developmental mechanisms of pediatric disease, allowing this research and educational program to encompass all pediatric disciplines. This application integrates the resources of the University of Utah and the Department of Pediatrics to establish a new, multidisciplinary program that will prepare promising physician-scientists for careers in academic pediatrics. Resources unique to this program include the established records of the research mentors, the Eccles Institute of Human Genetics, the Utah Birth Defects Network, and the Utah Population Database, an extensive genealogical database with more than 3 million records. The program will enable productive, well-funded investigators from several programs and departments to participate in the education of pediatric physician-scientists. Mentors and advisors for this program have been selected from the Program in Human Molecular Biology, the Department of Neurobiology and Anatomy, the Howard Hughes Medical Institute, the Huntsman Cancer Institute, the Department of Pathology, the Department of Biology, the Department of Human Genetics, and the Department of Pediatrics. Promising scholars will be selected from current faculty, fellows, and targeted recruitments. Didactic material, facilitated through an NIH-funded training program in the Inherited Basis of Human Disease, will provide graduate level education in biostatistics, study design, ethical issues, molecular biology, genetics, and medical writing. This program will enable the Department of Pediatrics to provide the education and protected mentored research support essential to the development of successful pediatric physician-scientists.

描述（由申请人提供）：此申请描述犹他大学CHRCDA项目。该计划广泛关注儿科疾病的遗传和发育机制，使该研究和教育计划涵盖所有儿科学科。该应用程序整合了犹他大学和儿科部门的资源，建立了一个新的多学科项目，将为学术儿科的职业生涯准备有前途的内科科学家。该项目独有的资源包括研究导师的既定记录、埃克尔斯人类遗传学研究所、犹他州出生缺陷网络和犹他州人口数据库（一个拥有300多万条记录的广泛的家谱数据库）。该项目将使来自多个项目和部门的富有成效、资金充足的研究人员参与儿科医师科学家的教育。这个项目的导师和顾问是从人类分子生物学项目、神经生物学和解剖学部门、霍华德休斯医学研究所、亨茨曼癌症研究所、病理学部门、生物系、人类遗传学部门和儿科部门中挑选出来的。有前途的学者将从现有的教师、研究员和有针对性的招聘中选出。通过美国国立卫生研究院资助的人类疾病遗传基础培训项目，教学材料将提供生物统计学、研究设计、伦理问题、分子生物学、遗传学和医学写作等研究生水平的教育。该项目将使儿科部门能够提供教育和受保护的指导研究支持，这对成功的儿科医生和科学家的发展至关重要。