Genetic and Developmental Mechanisms of Pediatric Disease

儿科疾病的遗传和发育机制

• 批准号: 7744044
• 负责人: Edward Bowersox Clark
• 金额: $ 43.2万
• 依托单位: UNIVERSITY OF UTAH
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-04-11 至 2012-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7744044
• 关键词: Award; Biometry; Child health care; Childhood; Developmental Biology; Disease; Education; Educational Curriculum; Environment; Epidemiology; Exploratory/Developmental Grant for Diagnostic Cancer Imaging; Faculty; Funding; Goals; Grant; Instruction; K-Series Research Career Programs; Laboratories; Lead; Medical Genetics; Mentors; Molecular Biology; Molecular Genetics; Physicians; Research; Research Ethics; Research Methodology; Research Personnel; Resources; Scientist; Series; Structure; Training; Training Programs; Universities; Utah; Writing; career; data management; developmental genetics; experience; improved; innovation; laboratory facility; medical schools; member; pediatric department

DESCRIPTION (provided by applicant): The Department of Pediatrics of the University of Utah proposes the continuation of its highly successful training program-the Utah Child Health Research Career Development Award (CHRCDA) program. The Utah CHRCDA selects the most outstanding junior faculty scholars for rigorous scientific training in a robust research environment. The Utah CHRCDA uses experienced basic- and physician-scientists as mentors to provide the expertise, guidance, and laboratory facilities that enable scholars to launch successful careers as physician-scientists. The overarching theme of the Utah CHRCDA, the genetic and developmental mechanisms that underlie pediatric disease, offers rich opportunities for research and discovery that will lead to improved health for children. Highly-promising scholars are selected from graduating fellows who join the Department, by faculty recruitment or from current junior faculty. Mentored experiences in the laboratories of established, NIH-funded investigators enable scholars to apply innovative research methods to molecular genetics and developmental biology. A structured curriculum (supported by a K30 award to the University's School of Medicine) offers scholars a graduate-level didactic education in epidemiology, biostatistics, data management, medical genetics, and molecular biology. Senior pediatric faculty members provide formal instruction in scientific writing, grant writing and research ethics. Utah scholars have made exceptional progress during the first four years of the current CHRCDA program. Four of the first six scholars received K series awards; one scholar has received an R21 award; and one scholar has a pending resubmission of a K08 application. These results indicate that the resources entrusted to the University of Utah and the Department of Pediatrics have been used effectively to mentor the research careers of young faculty members and fulfill the goals of the CHRCDA program.

描述(由申请人提供)：犹他大学儿科系建议继续其非常成功的培训计划-犹他州儿童健康研究职业发展奖(CHRCDA)计划。犹他州CHRCDA挑选最优秀的初级教员学者，在健全的研究环境中进行严格的科学培训。犹他州CHRCDA使用经验丰富的基础科学家和内科科学家作为导师，提供专业知识、指导和实验室设施，使学者能够作为内科科学家开始成功的职业生涯。犹他州CHRCDA的总体主题，即儿童疾病背后的遗传和发育机制，提供了丰富的研究和发现机会，将导致改善儿童的健康。非常有前途的学者是从即将毕业的研究员中挑选出来的，他们是通过招聘教员或从现有的初级教员中挑选出来的。在NIH资助的知名研究人员的实验室中的指导经验使学者能够将创新的研究方法应用于分子遗传学和发育生物学。一个结构化的课程(由大学医学院的K30奖项支持)为学者提供流行病学、生物统计学、数据管理、医学遗传学和分子生物学方面的研究生水平的教学教育。儿科资深教员提供科学写作、拨款写作和研究伦理方面的正式指导。犹他州学者在当前CHRCDA计划的前四年取得了非凡的进展。前六名中有四名获得了K系列奖；一名获奖者获得了R21奖；一名获奖者正在等待重新提交K08申请。这些结果表明，委托给犹他大学和儿科系的资源已经有效地用于指导年轻教职员工的研究生涯，并实现了CHRCDA计划的目标。