Genetic and Developmental Mechanisms of Pediatric Disease
Genetic and Developmental Mechanisms of Pediatric Disease
批准号:
8197130
负责人:
Edward Bowersox Clark
金额:
$43.2万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2003
资助国家:
美国
项目状态:
已结题
起止时间:
2003-04-11 至 2013-11-30
关键词:
AwardBiometryChild health careChildhoodDevelopmental BiologyDiseaseEducational CurriculumEnvironmentEpidemiologyExploratory/Developmental Grant for Diagnostic Cancer ImagingFacultyFundingGoalsGrantInstructionK-Series Research Career ProgramsLaboratoriesLeadMedical GeneticsMentorsMolecular BiologyMolecular GeneticsPhysiciansResearchResearch EthicsResearch MethodologyResearch PersonnelResourcesScientistSeriesStructureTrainingUnited States National Institutes of HealthUniversitiesUtahWritingcareerdata managementdevelopmental geneticsdidactic educationexperienceimprovedinnovationmedical schoolsmemberpediatric department
中文摘要
犹他大学儿科系建议继续其非常成功的研究
培训计划——犹他州儿童健康研究职业发展奖(CHRCDA)计划。的
犹他州 CHRCDA 选拔最优秀的初级教师学者,在强有力的环境中进行严格的科学培训
研究环境。犹他州 CHRCDA 使用经验丰富的基础科学家和医师科学家作为导师
提供专业知识、指导和实验室设施,使学者能够成功开展职业生涯
医生科学家。犹他州 CHRCDA 的首要主题是遗传和发育
儿科疾病背后的机制,为研究和发现提供了丰富的机会,这将导致
改善儿童的健康。高度有前途的学者是从加入该学院的毕业生中挑选出来的
部门,由教员招聘或从现任初级教员中挑选。实验室指导经验
NIH 资助的研究人员使学者能够将创新的研究方法应用于分子生物学
遗传学和发育生物学。结构化课程(由大学 K30 奖项支持)
医学院)为学者提供流行病学、生物统计学、数据方面的研究生水平教学教育
管理学、医学遗传学和分子生物学。高级儿科教师提供正式的
科学写作、资助写作和研究伦理方面的指导。犹他州的学者做出了杰出的贡献
当前 CHRCDA 计划头四年的进展。前六名学者中有四人获得 K
系列奖项;一名学者获得R21奖;一名学者正在等待重新提交一份
K08申请。这些结果表明,委托给犹他大学和
儿科系被有效地用来指导年轻教师的研究生涯
成员并实现 CHRCDA 计划的目标。
英文摘要
The Department of Pediatrics of the University of Utah proposes the continuation of its highly successful
training program¿the Utah Child Health Research Career Development Award (CHRCDA) program. The
Utah CHRCDA selects the most outstanding junior faculty scholars for rigorous scientific training in a robust
research environment. The Utah CHRCDA uses experienced basic- and physician-scientists as mentors to
provide the expertise, guidance, and laboratoryfacilities that enable scholars to launch successful careers as
physician-scientists. The overarching theme of the Utah CHRCDA, the genetic and developmental
mechanisms that underlie pediatric disease, offers rich opportunities for research and discovery that will lead
to improved health for children. Highly-promising scholars are selected from graduating fellows who join the
Department, by faculty recruitment or from current junior faculty. Mentored experiences in the laboratories of
established, NIH-funded investigators enable scholars to apply innovative research methods to molecular
genetics and developmental biology. A structured curriculum (supported by a K30 award to the University's
School of Medicine) offers scholars a graduate-level didactic education in epidemiology, biostatistics, data
management, medical genetics, and molecular biology. Senior pediatric faculty members provide formal
instruction in scientific writing, grant writing and research ethics. Utah scholars have made exceptional
progress during the first four years of the current CHRCDA program. Four of the first six scholars received K
series awards; one scholar has received an R21 award; and one scholar has a pending resubmission of a
K08 application. These results indicate that the resources entrusted to the University of Utah and the
Department of Pediatrics have been used effectively to mentor the research careers of young faculty
members and fulfill the goals of the CHRCDA program.
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Traumatic brain injury during development reduces minimal clonic seizure thresholds at maturity.
发育过程中的创伤性脑损伤会降低成熟时的阵挛性癫痫发作的最低阈值。
DOI:
10.1016/j.eplepsyres.2008.04.001
发表时间:
2008
期刊:
Epilepsy research
影响因子:
2.2
作者:
[Statler,KimberlyD, Swank,Seth, Abildskov,Tracy, Bigler,ErinD, White,HSteve]
通讯作者:
White,HSteve
DOI:
10.3389/fonc.2011.00039
发表时间:
2011
期刊:
Frontiers in oncology
影响因子:
4.7
作者:
[Luo W, Kinsey M, Schiffman JD, Lessnick SL]
通讯作者:
Lessnick SL
DOI:
10.1016/j.jpeds.2009.10.048
发表时间:
2010-03
期刊:
JOURNAL OF PEDIATRICS
影响因子:
5.1
作者:
[Blaschke, Anne J., Pulver, Laurie S., Korgenski, E. Kent, Savitz, Lucy A., Daly, Judy A., Byington, Carrie L.]
通讯作者:
Byington, Carrie L.
DOI:
10.1016/j.braindev.2018.01.003
发表时间:
2018-05
期刊:
Brain & development
影响因子:
1.7
作者:
[Schober ME, Requena DF, Rodesch CK]
通讯作者:
Rodesch CK
DOI:
10.1371/journal.pone.0043968
发表时间:
2012
期刊:
PloS one
影响因子:
3.7
作者:
[Xing L, Hoshijima K, Grunwald DJ, Fujimoto E, Quist TS, Sneddon J, Chien CB, Stevenson TJ, Bonkowsky JL]
通讯作者:
Bonkowsky JL
共 14 条
Early Life Exposures and Child Trajectories: Growth and Respiratory Health
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批准号:9261842
-
项目类别:
-
资助金额:$141.74万
-
财政年份:2016
-
负责人:Edward Bowersox Clark
-
依托单位:
Genetic and Developmental Mechanisms of Pediatric Disease
-
批准号:7991845
-
项目类别:
-
资助金额:$42.7万
-
财政年份:2003
-
负责人:Edward Bowersox Clark
-
依托单位:
Genetic and Developmental Mechanisms of Pediatric Disea*
-
批准号:6998904
-
项目类别:
-
资助金额:$43.03万
-
财政年份:2003
-
负责人:Edward Bowersox Clark
-
依托单位:
Genetic and Developmental Mechanisms of Pediatric Disease
-
批准号:7385400
-
项目类别:
-
资助金额:$43.2万
-
财政年份:2003
-
负责人:Edward Bowersox Clark
-
依托单位:
Genetic and Developmental Mechanisms of Pediatric Disease
-
批准号:7617631
-
项目类别:
-
资助金额:$43.2万
-
财政年份:2003
-
负责人:Edward Bowersox Clark
-
依托单位:
Genetic and Developmental Mechanisms of Pediatric Diseases
-
批准号:7157598
-
项目类别:
-
资助金额:$43.2万
-
财政年份:2003
-
负责人:Edward Bowersox Clark
-
依托单位:
Genetic and Developmental Mechanisms of Pediatric Disease
-
批准号:7744044
-
项目类别:
-
资助金额:$43.2万
-
财政年份:2003
-
负责人:Edward Bowersox Clark
-
依托单位:
Genetic and Developmental Mechanisms of Pediatric Disea*
-
批准号:6869599
-
项目类别:
-
资助金额:$42.27万
-
财政年份:2003
-
负责人:Edward Bowersox Clark
-
依托单位:
Genetic /Developmental Mechanisms of Pediatric Diseases
-
批准号:6571631
-
项目类别:
-
资助金额:$43.09万
-
财政年份:2003
-
负责人:Edward Bowersox Clark
-
依托单位:
Genetic and Developmental Mechanisms of Pediatric Disea*
-
批准号:6736318
-
项目类别:
-
资助金额:$43.2万
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财政年份:2003
-
负责人:Edward Bowersox Clark
-
依托单位:
HEART RATE AND BLOOD FLOW VELOCITY VARIABILITY IN HUMAN EMBRYO AND FETUS
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批准号:6110269
-
项目类别:
-
资助金额:$19.41万
-
财政年份:1998
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负责人:Edward Bowersox Clark
-
依托单位:
HEART RATE AND BLOOD FLOW VELOCITY VARIABILITY IN HUMAN EMBRYO AND FETUS
-
批准号:6242277
-
项目类别:
-
资助金额:$18.72万
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财政年份:1997
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负责人:Edward Bowersox Clark
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依托单位:
SCOR IN PEDIATRIC CARDIOVASCULAR DISEASE
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批准号:2228305
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项目类别:
-
资助金额:$107.33万
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财政年份:1994
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负责人:Edward Bowersox Clark
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依托单位:
SCOR IN PEDIATRIC CARDIOVASCULAR DISEASE
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批准号:2228306
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项目类别:
-
资助金额:$108.5万
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财政年份:1994
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负责人:Edward Bowersox Clark
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依托单位:
FUNCTION-STRUCTURE RELATION IN VENTRICULAR DEVELOPMENT
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批准号:3360230
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项目类别:
-
资助金额:$19.38万
-
财政年份:1988
-
负责人:Edward Bowersox Clark
-
依托单位:
FUNCTION-STRUCTURE RELATION IN VENTRICULAR DEVELOPMENT
-
批准号:3360231
-
项目类别:
-
资助金额:$17.58万
-
财政年份:1988
-
负责人:Edward Bowersox Clark
-
依托单位:
FUNCTION-STRUCTURE RELATION IN VENTRICULAR DEVELOPMENT
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批准号:3360234
-
项目类别:
-
资助金额:$17.45万
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财政年份:1988
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负责人:Edward Bowersox Clark
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依托单位:
FUNCTION-STRUCTURE RELATION IN VENTRICULAR DEVELOPMENT
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批准号:3360233
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项目类别:
-
资助金额:$16.46万
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财政年份:1988
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负责人:Edward Bowersox Clark
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依托单位:
FUNCTION-STRUCTURE RELATION IN VENTRICULAR DEVELOPMENT
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批准号:3360232
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项目类别:
-
资助金额:$16.15万
-
财政年份:1988
-
负责人:Edward Bowersox Clark
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依托单位:
海外基金