The Rapid-Production of the High-Performance and Affordable Cadmium Telluride and Cadmium Zinc Telluride for Medical Imaging Applications.

快速生产用于医学成像应用的高性能且经济实惠的碲化镉和碲化镉锌。

• 批准号: 10761330
• 负责人: LARS R FURENLID
• 金额: $ 102.49万
• 依托单位: RADIATION DETECTION TECHNOLOGIES, INC.
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-22 至 2025-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10761330
• 关键词: Acceleration; Businesses; CdZnTe; Chlorine; Clinical; Collection; Commercial grade; Densitometry; Dental; Detection; Devices; Diagnostic Imaging; Discipline of Nuclear Medicine; Gamma Rays; Government; Growth; Hour; Hybrids; Image; Imaging Device; Industrialization; Industry; Laboratory Research; Marketing; Medical; Medical Imaging; Methods; Oncology; Outcome; Pattern; Performance; Phase; Photons; Positron-Emission Tomography; Price; Process; Production; Property; Radiation; Radiation Dose Unit; Resolution; Roentgen Rays; Rotation; Security; System; Techniques; Temperature; Time; Travel; United States; United States National Institutes of Health; Validation; X-Ray Computed Tomography; X-Ray Medical Imaging; bone; cadmium telluride; commercialization; cost; crystallinity; design; imaging system; improved; instrumentation; interest; manufacture; melting; next generation; operation; prototype; radiation detector; technological innovation

1 The high spatial-resolution and energy-resolution of cadmium zinc telluride (CZT) and cadmium telluride 2 (CdTe), compared to that of scintillators, offers superior image quality in Nuclear medicine and X-ray 3 imaging applications, i.e. SPECT, PET, CT, Bone Densitometry, Oncology, Dental imaging, Airport 4 security, etc. CZT and CdTe remain the desired choice for room-temperature radiation detection, but it is 5 limited by high-cost and availability resulting from low yield and long production times associated with 6 commercial growth techniques, i.e. the Traveling Heater Method (THM). However, the application of the 7 Accelerated Crucible Rotation Technique (ACRT) growth method developed at WSU has proven to 8 produce industrial quality, high-performance CdTe/CZT. This recently developed growth method not only 9 allows CdTe/CZT to be grown with the same quality as material grown by THM, but also at growth rates 10 approximately 10-20 times faster than THM. Specifically, CdTe/CZT is grown by THM at a rate of 11 approximately 1-3 mm per day, whereas CdTe/CZT growth by ACRT can be accomplished at much faster 12 rates of approximately 1-3 mm per hour. THM-grown CdTe/CZT requires a lower growth temperature for 13 high-quality devices, which results in highly off-stoichiometric melts, thereby inducing the need for 14 postprocessing. These major challenges associated with the crystal growth of CdTe/CZT have been 15 overcome using ACRT. It is proposed here to further develop the ACRT growth process by introducing 16 crystal seeding in the ACRT system for CdTe and scale this process to commercial-grade levels while 17 continuing to improve the CdTe device properties for high-flux SPECT/CT applications. Chlorine doping 18 will be further explored and optimized to achieve high resistivity and high mobility-lifetime CdTe devices. 19 Numerous CdTe:Cl ingots will be grown, and devices will be produced from these ingots (cross strip and 20 commercial pixel patterns). Devices will be sent to commercial partners and customers for validation in 21 effort to integrate into commercial imaging systems. A prototype SPECT/CT system will be designed, built, 22 and images will be collected. The medical/diagnostic imaging market is projected to cross $55.7 billion by 23 2025. Stakeholders in the medical imaging market need CdTe/CZT devices now. The fruition of this project 24 will be a significant reduction (>3x) of industrial-grade material costs by increasing the yield, reducing the 25 growth time, and eliminating post-growth anneal treatments currently used by industry. With the fast- 26 production time and high-performance of the CdTe/CZT produced in this effort, (1) the medical imaging 27 market will finally have a fast turnaround time and consistent high-performance material that can easily be 28 obtained, (2) a >3x price reduction is projected for CdTe/CZT, and (3) Stakeholders will have access to an 29 affordable, high-performance CdTe/CZT material that can be obtained for imaging instrumentation and 30 other radiation detection applications.

1碲化镉锌（CZT）和碲化镉的高空间分辨率和高能量分辨率