Recharge Behavioral Therapy for caregivers of individuals with Alzheimer's Disease

为阿尔茨海默病患者的护理人员提供充电行为疗法

• 批准号: 10761621
• 负责人: BRUNO KAJIYAMA
• 金额: $ 49.34万
• 依托单位: PHOTOZIG, INC.
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-05 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10761621
• 关键词: Address; Alzheimer' s Disease; Alzheimer' s disease care; Alzheimer' s disease caregiver; Alzheimer' s disease patient; American; Anxiety; Apple; Behavior; Behavior Therapy; Behavioral; Calendar; Caregivers; Caring; Charge; Clinical Trials; Cognitive; Complement; Coping Skills; Creativeness; Data; Dementia; Dementia caregivers; Development; Distress; Educational Curriculum; Educational process of instructing; Effectiveness; Effectiveness of Interventions; Emotional; Emotions; Environment; Evaluation; Event; Family; Family Caregiver; Family member; Fees; Focus Groups; Fostering; Goals; Health; Home; Hybrids; Incidence; Individual; Institutionalization; Intervention; Learning; Link; Literature; Location; Marketing; Mental Depression; Methods; Moods; Music; Notification; Outcome; Patients; Personal Satisfaction; Personality; Persons; Pharmaceutical Preparations; Phase; Play; Protocols documentation; Publishing; Quality of life; Randomized; Reporting; Research; Rewards; Role; Services; Stress; Symptoms; Testing; Therapeutic Intervention; Time; Training; Training Programs; Translating; Well in self; care burden; care systems; caregiver stress; caregiving; chronic pain; coping; cost; cost effective intervention; dementia caregiving; depressive symptoms; design; economic cost; effective therapy; evidence base; feasibility testing; flexibility; high risk; improved; informal care; innovation; mindfulness; mindfulness intervention; mobile application; online care; prevent; programs; prototype; psychoeducation; psychoeducational; public health relevance; randomized, clinical trials; recruit; recurrent depression; relapse prevention; skills; social; stress management; stress reduction; stress symptom; usability

Project Summary Caring for individuals with Alzheimer's Disease (AD) is associated with depressive symptoms and “burden” because dealing with AD patient's cognitive, behavioral and personality changes is very challenging and stressful for caregivers. There are over 11 million AD caregivers in the US, providing informal care services to family members, with high incidences of stress (59%) and depressive symptoms (30%). Clinical trials and other academic research demonstrated the benefits of non-pharmacological interventions to improve the psychological well-being of AD caregivers, however there is a recognized need to translate these programs to accessible products/services and deliver them widely at minimum cost. To address these needs, we propose the new Recharge Behavioral Therapy (RBT), derived from an evidence- based protocol to treat depression (Behavioral Activation) and a proven program to train coping skills (Coping With Caregiving). We will translate prior research, combine powerful behavioral activation methods, and tailor the integrated curriculum for AD caregivers into a new intervention to reduce stress and depressive symptoms. Besides being an effective treatment for depression (efficacy stablished by multiple clinical trials), Behavioral Activation (BA) was selected because it motivates individuals to engage in healthy behaviors to improve their wellness. AD caregivers usually sacrifice their own physical and emotional needs, when providing care. The BA component will encourage caregivers to take care of their own well-being and “Recharge their energy” in their caregiving journey, so that they can fulfil their caregiver role at their best and improve their quality of life. Coping With Caregiving (CWC) is a psychoeducational training program for AD caregivers, evaluated in several clinical trials with demonstrated effectiveness in decreasing caregiver distress, burden of care, stress, and depression. By integrating CWC in RBT, we will provide the necessary consideration to the AD caregiving context and the resulting intervention will contain beneficial coping strategies for AD caregivers. Furthermore, the implementation mechanism for the RBT intervention will be the new Recharge Mobile App (RMA), an interactive, easy to use, and engaging mobile app that can be deployed to millions of people on demand (app install from app stores) and at very low cost (small subscription fee). RMA will be tailored for AD caregivers with training, practices, and content for RBT, which is not available in the market. Creative use of app features (interactivity, compliance, and notifications) will engage caregivers. Phase I will determine the initial RBT curriculum, develop the RMA prototype, and evaluate the feasibility. Phase II will fully develop RBT/RMA and evaluate the intervention effectiveness with a randomized clinical trial. RMA will help to reduce caregiver stress and depressive symptoms related to AD caregiving with a non- pharmacological approach; offering an effective, low-cost, and accessible mobile app to be disseminated to innumerous families struggling with Alzheimer's Disease through Apple and Google Play app stores.

项目摘要 照顾阿尔茨海默病（AD）患者与抑郁症状和“负担”有关 因为处理AD患者的认知、行为和人格变化非常具有挑战性， 对看护者来说压力很大。美国有超过1100万AD护理人员，为以下人群提供非正式护理服务： 家庭成员中，压力（59%）和抑郁症状（30%）的发生率较高。 临床试验和其他学术研究证明了非药物干预的益处， 改善AD护理人员的心理健康，但人们认识到需要将这些 以最低的成本广泛提供产品/服务。 为了满足这些需求，我们提出了新的充电行为疗法（RBT），来自证据- 基于协议来治疗抑郁症（行为激活）和经过验证的程序，以训练应对技能（应对 照顾）。我们将翻译先前的研究，联合收割机强大的行为激活方法， 综合课程的AD照顾者到一个新的干预，以减少压力和抑郁症状。 除了是一种有效的治疗抑郁症（疗效由多个临床试验确立），行为 选择激活（BA）是因为它激励个人参与健康的行为，以提高他们的健康水平。 健康AD照顾者在提供护理时通常会牺牲自己的身体和情感需求。的 BA部分将鼓励照顾者照顾自己的福祉，并在 他们的成长旅程，使他们能够履行其照顾者的角色，在他们最好的，并提高他们的生活质量。 应对护理（CWC）是一项针对AD护理人员的心理教育培训计划， 几项临床试验证明了在减少护理者痛苦、护理负担、压力 和抑郁症通过将《化学武器公约》纳入RBT，我们将为反倾销提供必要的考虑 背景和由此产生的干预将包含有益的应对策略，AD照顾者。 此外，RBT干预的实施机制将是新的Recharge移动的App (RMA)，这是一款交互式、易于使用且具有吸引力的移动的应用程序，可部署到 需求（从应用程序商店安装应用程序）和非常低的成本（小额订阅费）。 RMA将为AD护理人员量身定制，提供RBT的培训、实践和内容， 市场创造性地使用应用程序功能（交互性、合规性和通知）将吸引护理人员。 第一阶段将确定最初的RBT课程，开发RMA原型，并评估可行性。 第二阶段将全面开发RBT/RMA，并通过随机临床试验评估干预有效性。 RMA将有助于减少照顾者的压力和抑郁症状，与非AD患者相关。 药理学方法;提供有效、低成本和可访问的移动的应用程序， 通过Apple和Google Play应用商店帮助无数与阿尔茨海默病作斗争的家庭。