Targeting Therapeutic Gene Vectors to Reactive Glia
Targeting Therapeutic Gene Vectors to Reactive Glia
批准号:
7383150
负责人:
JIANFENG XU
金额:
$5.86万
依托单位国家:
美国
项目类别:
财政年份:
2007
资助国家:
美国
项目状态:
已结题
起止时间:
2007-03-26 至 2010-03-25
关键词:
Animal ModelAstrocytesBasic ScienceBrainBrain DiseasesCapsidCapsid ProteinsEngineeringEpitopesFacility Construction Funding CategoryGene ExpressionGene TargetingGene-ModifiedGenerationsGenesIn VitroIschemiaModelingNeurogliaNeuronsPurposeRattusRoleSatellite VirusesSpecificityStandards of Weights and MeasuresTestingTherapeuticTransient Cerebral Ischemiaadeno-associated viral vectorchemokine receptorcytokineefficacy evaluationin vivoinjurednervous system disorderneuron lossnovelreceptor bindingresponsesmall hairpin RNAtargeted deliverytherapeutic genetoolvector
中文摘要
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英文摘要
DESCRIPTION (provided by applicant): The objective of this proposal is to generate a novel set of targeted gene vectors with specificity for reactive glial cells, which will serve as valuable tools for basic research into the mechanisms underlying multiple brain disorders as well as vehicles for potential therapy, and test them in a specific first application to a standard animal model of ischemia.
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Targeting Therapeutic Gene Vectors to Reactive Glia
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批准号:7586677
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项目类别:
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资助金额:$5.86万
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财政年份:2007
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负责人:JIANFENG XU
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依托单位:
Targeting Therapeutic Gene Vectors to Reactive Glia
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批准号:7158017
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项目类别:
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资助金额:$5.8万
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财政年份:2007
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负责人:JIANFENG XU
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依托单位:
国内基金
海外基金
Ascl1介导Wnt/beta-catenin通路在TLE海马硬化中反应性Astrocytes异常增生的作用及调控机制
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批准号:31760279
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项目类别:地区科学基金项目
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资助金额:35.0万元
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批准年份:2017
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负责人:丁银秀
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依托单位: