Metabolic control of innate-like lymphocytes

先天样淋巴细胞的代谢控制

• 批准号: nhmrc : 1047615
• 负责人: Prof Alan Baxter
• 金额: $ 41.78万
• 依托单位: James Cook University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/metabolic-control-innate-like-lymphocytes/111951
• 关键词: Metabolic; control; innate; like; lymphocytes

All cells in the body need to get their energy from somewhere, and the chemical basis of their energy supply varies depends on many factors, including their location and rate of cell division. We have found that an important population of white blood cells that control the character and magnitude of most immune responses appear to use an unusual source of their energy. If true this would provide a range of new opportunities to control the numbers and activities of these cells, a thereby control the character and magnitude of immune responses.

身体中的所有细胞都需要从某个地方获得能量，它们能量供应的化学基础取决于许多因素，包括它们的位置和细胞分裂的速度。我们发现，控制大多数免疫反应性质和强度的重要白细胞群似乎使用了一种不寻常的能量来源。如果这是真的，这将提供一系列新的机会来控制这些细胞的数量和活动，从而控制免疫反应的性质和程度。