Metabolic and Neurobiological changes after Continuous Positive Airway Pressure treatment for Obstructive Sleep Apnea

持续气道正压通气治疗阻塞性睡眠呼吸暂停后的代谢和神经生物学变化

• 批准号: nhmrc : 512498
• 负责人: A/Pr Brendon Yee
• 金额: $ 33.57万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/metabolic-neurobiological-changes-sleep-apnea/81191
• 关键词: Metabolic; Neurobiological; changes; after; Continuous

CPAP is the preferred treatment for patients with OSA because of its well-proven ability to decrease sleepiness and improve blood pressure control. This study will definitively establish if CPAP can also improve markers of cardio-metabolic health, such as visceral fat, insulin sensitivity, central blood pressure and arterial stiffness. The results of the study will shed light on the broader health consequences of OSA and contribute to the development of more targeted treatment strategies.

CPAP是OSA患者的首选治疗方法，因为它被证明能够减少嗜睡和改善血压控制。这项研究将明确确定CPAP是否也可以改善心脏代谢健康的标志物，如内脏脂肪，胰岛素敏感性，中心血压和动脉僵硬度。这项研究的结果将揭示OSA的更广泛的健康后果，并有助于制定更有针对性的治疗策略。