Minority-Based CCOP at UMDNJ-NJ Medical School/University Hospital Cancer Center

描述（由申请人提供）：我们提议在新泽西医学和牙科大学-新泽西医学院/大学医院癌症中心建立一个以少数民族为基础的社区临床肿瘤项目。我们服务的患者群体主要来自纽瓦克的内城社区，周边城镇和埃塞克斯县的城市社区。患者中超过60%是非裔美国人和拉丁裔美国人，他们的收入低得不成比例，贫困率高，癌症死亡率高。大学医院肿瘤登记处每年记录了超过1100例新的癌症病例，其中头颈癌、肝癌和宫颈癌的发病率高得不成比例。我们也看到很多乳腺癌、胃肠道、前列腺癌、肺癌和脑瘤的病例。癌症中心的医生通过合作提供团队治疗方法。每个新患者都在9个疾病特异性肿瘤委员会或大查房之一进行报告。癌症中心社区在拓展周边社区方面有着非凡的记录，其项目包括消除健康差距研究所、社区改善健康伙伴关系、通过癌症控制委员会开展的筛查和教育项目、埃塞克斯价值筛查（S.A.V.E.）移动筛查项目、妇女健康倡议预防研究、补充和替代医学研究所、改善少数民族和医疗服务不足的癌症临床试验的参与和获取（IMPACT）和埃塞克斯县联盟，所有这些都承诺招募少数民族患者参加我们的MBCCOP研究。我们建议通过MBCCOP开展一个协调的研究项目，开放来自9个研究基地的43多项预防/控制和治疗试验，为大多数肿瘤类型提供临床方案。我们的癌症中心临床研究办公室及其工作人员在积累和维持少数民族患者的研究方面拥有丰富的经验。我们将扩展一种使用患者研究导航员的新方法，这些导航员来自与患者沟通并建立信任的社区。这导致临床试验的应计费用增加。我们概述了一个模型，该模型将确保每年有超过50名少数民族患者获得预防/控制和治疗方案。

DESCRIPTION (provided by applicant): We are proposing to establish a Minority-Based Community Clinical Oncology Program at the University of Medicine and Dentistry of New Jersey-New Jersey Medical School/University Hospital Cancer Center. We serve a patient population which is primarily from the inner city neighborhoods of Newark, surrounding towns and urban communities of Essex County. The patients are more than 60% African American and Latino, have disproportionately low income, high poverty rates and high mortality from cancer. The University Hospital Tumor Registry records over 1100 new cancer cases a year, with disproportionately high incidence of head and neck, liver, and cervical cancer. We also see a high number of cases with breast, gastrointestinal, prostate, lung and brain tumors. The Cancer Center physicians work in collaboration to provide a team approach to therapy. Each new patient is presented at one of 9 disease-specific tumor boards or Grand Rounds. The Cancer Center Community has an extraordinary track record in outreach to the surrounding community with programs that include the Institute for the Elimination of Health Disparities, Community Partnership for Better Health, screening and education programs through the Cancer Control Committee, Screening Access of Value to Essex (S.A.V.E.) mobile screening program, the Women's Health Initiative prevention studies, the Institute for Complementary and Alternative Medicine, Improving Minority and Medically Under-Served Participation and Access in Cancer Clinical Trials (IMPACT) and the Essex County Coalition, all of which have pledged to recruit minority patients to our MBCCOP studies. We propose to develop a coordinated research program through the MBCCOP by opening more than 43 prevention/control and treatment trials from 9 research bases to make available clinical protocols for most tumor types. Our Cancer Center Clinical Research Office and its staff have extensive experience with accruing and maintaining minority patients on studies. We will expand a novel approach of using patient study navigators form the community who communicate and develop trust with patients. This has resulted in an increase in accrual to clinical trials. We outlined a model that will ensure accrual of more than 50 minority patients a year each on prevention/control and on treatment protocols.