Minority-Based CCOP at UMDNJ-NJ Medical School/University Hospital Cancer Center

描述（由申请人提供）：我们建议在新泽西医学和牙科大学-新泽西医学院/大学医院癌症中心建立一个以少数民族为基础的社区临床肿瘤学项目。我们服务的患者人群主要来自纽瓦克的内城社区、埃塞克斯县的周边城镇和城市社区。患者中超过60%是非洲裔美国人和拉丁美洲人，收入不成比例地低，贫困率高，癌症死亡率高。大学医院肿瘤登记处每年记录超过1100例新发癌症病例，其中头颈部、肝癌和宫颈癌的发病率不成比例地高。我们还看到大量的乳腺癌、胃肠道肿瘤、前列腺肿瘤、肺癌和脑瘤病例。癌症中心的医生合作提供团队治疗方法。每个新患者都在9个疾病特异性肿瘤委员会或大圆桌会议之一上提出。癌症中心社区在与周围社区的外联方面有着非凡的记录，其项目包括消除健康差异研究所、改善健康的社区伙伴关系、通过癌症控制委员会开展的筛查和教育项目、埃塞克斯筛查价值访问（S.A.V.E.）移动的筛查计划，妇女健康倡议预防研究，补充和替代医学研究所，改善少数民族和医疗服务不足的参与和获得癌症临床试验（IMPACT）和埃塞克斯县联盟，所有这些都承诺招募少数民族患者参加我们的MBCCOP研究。我们建议通过MBCCOP开发一个协调的研究计划，从9个研究基地开放超过43个预防/控制和治疗试验，为大多数肿瘤类型提供临床方案。我们的癌症中心临床研究办公室及其工作人员在研究中积累和维护少数民族患者方面拥有丰富的经验。我们将扩展一种新的方法，使用来自社区的患者研究导航员，他们与患者进行沟通并建立信任。这导致临床试验的应计费用增加。我们概述了一个模式，该模式将确保每年有50多名少数民族患者接受预防/控制和治疗方案。

DESCRIPTION (provided by applicant): We are proposing to establish a Minority-Based Community Clinical Oncology Program at the University of Medicine and Dentistry of New Jersey-New Jersey Medical School/University Hospital Cancer Center. We serve a patient population which is primarily from the inner city neighborhoods of Newark, surrounding towns and urban communities of Essex County. The patients are more than 60% African American and Latino, have disproportionately low income, high poverty rates and high mortality from cancer. The University Hospital Tumor Registry records over 1100 new cancer cases a year, with disproportionately high incidence of head and neck, liver, and cervical cancer. We also see a high number of cases with breast, gastrointestinal, prostate, lung and brain tumors. The Cancer Center physicians work in collaboration to provide a team approach to therapy. Each new patient is presented at one of 9 disease-specific tumor boards or Grand Rounds. The Cancer Center Community has an extraordinary track record in outreach to the surrounding community with programs that include the Institute for the Elimination of Health Disparities, Community Partnership for Better Health, screening and education programs through the Cancer Control Committee, Screening Access of Value to Essex (S.A.V.E.) mobile screening program, the Women's Health Initiative prevention studies, the Institute for Complementary and Alternative Medicine, Improving Minority and Medically Under-Served Participation and Access in Cancer Clinical Trials (IMPACT) and the Essex County Coalition, all of which have pledged to recruit minority patients to our MBCCOP studies. We propose to develop a coordinated research program through the MBCCOP by opening more than 43 prevention/control and treatment trials from 9 research bases to make available clinical protocols for most tumor types. Our Cancer Center Clinical Research Office and its staff have extensive experience with accruing and maintaining minority patients on studies. We will expand a novel approach of using patient study navigators form the community who communicate and develop trust with patients. This has resulted in an increase in accrual to clinical trials. We outlined a model that will ensure accrual of more than 50 minority patients a year each on prevention/control and on treatment protocols.