Multifaceted Prospective Memory Intervention to Improve Medication Adherence
多方面的前瞻性记忆干预可提高药物依从性
基本信息
- 批准号:7579519
- 负责人:
- 金额:$ 48.1万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2008
- 资助国家:美国
- 起止时间:2008-09-30 至 2012-06-30
- 项目状态:已结题
- 来源:
- 关键词:AddressAdherenceAdultAgeAge-YearsAntihypertensive AgentsApplied ResearchAreaBehaviorBlood PressureCardiovascular systemCerebrovascular DisordersCessation of lifeChronicChronic DiseaseCognitiveCommunitiesConditionControl GroupsCuesDependenceDevelopmentDiseaseDoseEducationEffectivenessElderlyElectronicsEnvironmentEventHealth Care CostsHeart failureHigh Blood PressureHome environmentHypertensionHypotensionImpaired cognitionIndividualIntentionInterventionInvestigationLaboratoriesMeasuresMedicalMedicineMemoryMonitorPatientsPatternPerformancePharmaceutical PreparationsPhasePopulationProceduresProcessPsychological reinforcementPublic HealthPurposeQuality of lifeRandomizedRateResearchResourcesReview, Systematic (PT)RiskRisk ReductionScoreShort-Term MemorySocietiesStrokeTestingThinkingTimeTrainingVisitWeekWorld Health Organizationage relatedbaseblood pressure regulationcomparison groupcostdesigndisabilityexecutive functionexperiencehuman old age (65+)improvedinnovationmedication compliancemodifiable riskprescription documentprescription procedurepreventprospectiveprospective memorytask analysis
项目摘要
DESCRIPTION (provided by applicant): Adherence to medication is the single most important strategy to prevent high blood pressure and its subsequent deleterious and costly effects including stroke, heart failure and cognitive decline. Adherence is a significant problem in hypertension with estimates of only 50 percent appropriately adhering to their prescribed medications. Hypertension is also an asymptomatic chronic illness and therefore one without internal memory cues to medication taking. Hypertension is prevalent among older adults who have been shown to experience declines in cognitive processes that otherwise might compensate for the lack of internal cues to support adherence. The purpose of the proposed study is to test the effect of an in-home, tailored, multifaceted prospective memory intervention on adherence to antihypertensive medication for adults 65 years of age and older. The intervention is grounded in recent empirical and theoretical developments in the area of prospective memory and focuses on enhancing medication adherence through the use of relatively well-preserved cue- driven and automatic processes. Older adults who are self-managing at least one antihypertensive agent and are adherent to this medication less than or equal to 90 percent following 4 weeks of baseline monitoring, will be randomly assigned to one of two groups. One group will receive the intervention consisting of 4 phases: establishing a relationship, education, implementation of multifaceted strategies to improve prospective remembering and weekly reinforcement sessions for 3 weeks. The education comparison group will only receive part of the first and second phase of the intervention, establishing a relationship and education and will be visited for an additional 3 weeks similar to the visits for the intervention group, but will not receive strategy training. Adherence will be determined using Medication Electronic Monitoring. It is hypothesized that the intervention group will have greater overall adherence and that the relationship between overall adherence and executive function/working memory will be smaller than for the education comparison group because the intervention reduces the need for high levels of executive function to achieve adherence. Patterns of adherence will be assessed across a six-month period. A major public health consequence of this study is limiting disabilities among older adults because hypertension is associated with cognitive decline and cardiovascular and cerebrovascular disease including stroke. While this intervention is being tested with older adults, the intervention has broad implications for improving adherence in other populations. PUBLIC HEALTH RELEVANCE: Taking medications as prescribed is the single most important way to prevent the effects of high blood pressure. This study addresses the important public health problem of high blood pressure by testing an intervention to help people take medications as prescribed. If we can improve the way people take blood pressure medicines, we can improve the quality of life for older adults and decrease health care costs.
描述(由申请人提供):坚持用药是预防高血压及其后续有害和昂贵影响(包括中风、心力衰竭和认知能力下降)的最重要策略。依从性是高血压的一个重要问题,估计只有50%的人适当地依从他们的处方药物。高血压也是一种无症状的慢性疾病,因此没有服用药物的内部记忆线索。高血压在老年人中普遍存在,这些老年人已被证明会经历认知过程的下降,否则可能会弥补缺乏支持依从性的内部线索。这项研究的目的是测试一种家庭、定制、多方面的前瞻性记忆干预对65岁及以上成年人抗高血压药物依从性的影响。该干预基于前瞻性记忆领域的最新经验和理论发展,并侧重于通过使用相对保存良好的线索驱动和自动过程来增强药物依从性。自我管理至少一种抗高血压药物并且在4周基线监测后对该药物的依从性小于或等于90%的老年人将被随机分配到两组之一。一组将接受包括4个阶段的干预:建立关系,教育,实施多方面的策略以改善前瞻性记忆和每周强化会议,为期3周。教育对照组仅接受第一阶段和第二阶段的部分干预,建立关系和教育,并将接受额外3周的访问,类似于干预组的访问,但不接受策略培训。将使用药物电子监测确定依从性。假设干预组的总体依从性更高,并且总体依从性与执行功能/工作记忆之间的关系将小于教育对照组,因为干预减少了实现依从性对高水平执行功能的需求。将在6个月内评估依从性模式。这项研究的一个主要公共卫生后果是限制老年人的残疾,因为高血压与认知能力下降和心血管和脑血管疾病(包括中风)有关。虽然这种干预措施正在老年人中进行测试,但这种干预措施对改善其他人群的依从性具有广泛的影响。公共卫生相关性:按处方服药是预防高血压影响的最重要的方法。这项研究通过测试一种干预措施来帮助人们按处方服药,从而解决了高血压这一重要的公共卫生问题。如果我们能改善人们服用降压药的方式,我们就能提高老年人的生活质量,降低医疗保健费用。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
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KATHLEEN C INSEL其他文献
KATHLEEN C INSEL的其他文献
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{{ truncateString('KATHLEEN C INSEL', 18)}}的其他基金
Digital Technology to Support Adherence to Hypertension Medications for Older Adults with Mild Cognitive Impairment
数字技术支持患有轻度认知障碍的老年人坚持高血压药物治疗
- 批准号:
10363162 - 财政年份:2022
- 资助金额:
$ 48.1万 - 项目类别:
Digital Technology to Support Adherence to Hypertension Medications for Older Adults with Mild Cognitive Impairment
数字技术支持患有轻度认知障碍的老年人坚持高血压药物治疗
- 批准号:
10618618 - 财政年份:2022
- 资助金额:
$ 48.1万 - 项目类别:
Multifaceted Prospective Memory Intervention to Improve Medication Adherence
多方面的前瞻性记忆干预可提高药物依从性
- 批准号:
7839534 - 财政年份:2009
- 资助金额:
$ 48.1万 - 项目类别:
Multifaceted Prospective Memory Intervention to Improve Medication Adherence
多方面的前瞻性记忆干预可提高药物依从性
- 批准号:
7695022 - 财政年份:2008
- 资助金额:
$ 48.1万 - 项目类别:
Multifaceted Prospective Memory Intervention to Improve Medication Adherence
多方面的前瞻性记忆干预可提高药物依从性
- 批准号:
7877972 - 财政年份:2008
- 资助金额:
$ 48.1万 - 项目类别:
Multifaceted Prospective Memory Intervention to Improve Medication Adherence
多方面的前瞻性记忆干预可提高药物依从性
- 批准号:
8092862 - 财政年份:2008
- 资助金额:
$ 48.1万 - 项目类别:
Biological Age and Capacity for Self-Management: Implications for Nursing
生物年龄和自我管理能力:对护理的影响
- 批准号:
7256356 - 财政年份:2006
- 资助金额:
$ 48.1万 - 项目类别:
Biological Age and Capacity for Self-Management: Implications for Nursing
生物年龄和自我管理能力:对护理的影响
- 批准号:
7134805 - 财政年份:2006
- 资助金额:
$ 48.1万 - 项目类别:
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