MicroRNA pathway control of immune cell development

MicroRNA通路控制免疫细胞发育

• 批准号: nhmrc : 1117154
• 负责人: Dr Mark Chong
• 金额: $ 43.17万
• 依托单位: St. Vincent's Institute of Medical Research
• 依托单位国家: 澳大利亚
• 项目类别: Research Fellowships
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 2021-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/microrna-pathway-control-cell-development/946183
• 关键词: MicroRNA; pathway; control; immune; cell

The immune system is comprised of many different cell types, each with a specialised function. Many are short-lived and must be continually replenished throughout life. Abnormalities in this process underlie many human diseases, including immunodeficiency, autoimmunity and cancer. My laboratory seeks to understand the molecular pathways that control development of immune cells and to identify the defects that lead to disease.

免疫系统由许多不同类型的细胞组成，每种细胞都有专门的功能。许多是短暂的，必须在一生中不断补充。这一过程的异常是许多人类疾病的基础，包括免疫缺陷、自身免疫和癌症。我的实验室试图了解控制免疫细胞发育的分子途径，并确定导致疾病的缺陷。