Cell-specific regulation of the microRNA/RNAi pathway

microRNA/RNAi 通路的细胞特异性调控

• 批准号: nhmrc : 1079586
• 负责人: Dr Mark Chong
• 金额: $ 43.97万
• 依托单位: St. Vincent's Institute of Medical Research
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/cell-specific-regulation-micrornarnai-pathway/518677
• 关键词: Cell; specific; regulation; microRNA; RNAi

MicroRNAs are a group of molecules that are critical for controlling the activity of genes. They function in a diverse range of biological systems, such the brain and immune system. Although we know that these molecules are important, how they are made in cells is still poorly understood. Because these molecules have potential therapeutic applications, it is essential that we gain a precise understanding of their biology before we will be able to apply these to medicine.

MicroRNA是一组对控制基因活性至关重要的分子。它们在各种生物系统中发挥作用，如大脑和免疫系统。虽然我们知道这些分子很重要，但对它们在细胞中是如何产生的仍然知之甚少。由于这些分子具有潜在的治疗应用，因此在我们能够将其应用于医学之前，我们必须对其生物学进行精确的了解。