Cell-specific regulation of the microRNA/RNAi pathway

MicroRNAs是一组对控制基因活性至关重要的分子。它们在一系列不同的生物系统中发挥作用，如大脑和免疫系统。尽管我们知道这些分子很重要，但我们对它们在细胞中是如何制造的仍然知之甚少。由于这些分子具有潜在的治疗应用，在我们能够将它们应用于医学之前，我们必须对它们的生物学有一个准确的了解。

MicroRNAs are a group of molecules that are critical for controlling the activity of genes. They function in a diverse range of biological systems, such the brain and immune system. Although we know that these molecules are important, how they are made in cells is still poorly understood. Because these molecules have potential therapeutic applications, it is essential that we gain a precise understanding of their biology before we will be able to apply these to medicine.