A stem cell-specific microRNA-independent function of Drosha

干细胞负责产生和补充我们体内约200种特化细胞类型。我们的目标是了解控制这些细胞功能的分子开关。我们最近发现，干细胞内某些基因的活性是由降解控制的。这种降解对于保护干细胞的功能至关重要。这个项目将研究这部小说的机制是如何控制这些细胞内。

Stem cells are responsible for producing and replenishing the ~200 specialised cell types in our body. Our goal is to understand the molecular switches that control the function of these cells. We recently discovered that the activity of certain genes within stem cells is controlled by degradation. This degradation is absolutely crucial for safeguarding the function of stem cells. This project will investigate how this novel mechanism is controlled within these cells.