BIOPHYSICAL BASIS OF MUSCLE FUNCTIONAL MRI

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目及 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 肌肉功能磁共振成像（mfMRI），其中运动肌肉出现更高的信号强度（SI）比非运动肌肉，已被提出作为一种工具，用于检查肌肉的代谢和血液动力学反应的运动。然而，其机制基础仍不清楚。本研究的目的是提供一个全面的和定量的描述的生理和生物物理机制的基础mfMRI。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Muscle functional magnetic resonance imaging (mfMRI), in which exercising muscles appear with higher signal intensity (SI) than non-exercising muscles, has been proposed as a tool for examining the metabolic and hemodynamic responses of muscles to exercise. However, its mechanistic basis remains unclear. The purpose of this study is to provide a comprehensive and quantitative description of the physiological and biophysical mechanisms underlying mfMRI.