SURFACTANT POSITIVE AIRWAY PRESSURE AND PULSE OXIMETRY TRIAL IN ELBW INFANTS

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 研究人员希望确定是否可以通过使用持续正压(CPAP)和允许性机械通气策略来减少早产儿支气管肺发育不良(BPD)的发生率，而不是从产房开始自动气管插管、使用表面活性物质和传统的机械通气。他们还希望确定在这些婴儿中保持较低的氧饱和度是否会减少严重早产儿视网膜病变(ROP)的发生率。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The investigators hope to determine if the incidence bronchopulmonary dysplasia (BPD) can be reduced in premature infants by using continuous positive air pressure (CPAP) and a permissive ventilation strategy rather than automatic endotracheal intubation, surfactant administration, and conventional mechanical ventilation beginning in the delivery room. They also hope to determine if maintaining a lower oxygen saturation in these infants will reduce the incidence of significant retinopathy of prematurity (ROP).