SURFACTANT POSITIVE AIRWAY PRESSURE AND PULSE OXIMETRY TRIAL IN ELBW INFANTS

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This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The investigators hope to determine if the incidence bronchopulmonary dysplasia (BPD) can be reduced in premature infants by using continuous positive air pressure (CPAP) and a permissive ventilation strategy rather than automatic endotracheal intubation, surfactant administration, and conventional mechanical ventilation beginning in the delivery room. They also hope to determine if maintaining a lower oxygen saturation in these infants will reduce the incidence of significant retinopathy of prematurity (ROP).