ELBW

低体重儿

• 批准号: 7605154
• 负责人: DAVID K STEVENSON
• 金额: $ 0.41万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-02-15 至 2007-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7605154
• 关键词: Address; Age; Age-Months; Area; Behavior; Birth Weight; Caring; Childhood; Cognitive; Computer Retrieval of Information on Scientific Projects Database; Conflict (Psychology); Databases; Development; Early Intervention; Extremely Low Birth Weight Infant; Family; Funding; Generic Drugs; Grant; Growth; Health Policy; Institution; Language; Link; Literature; Medical; Methods; Morbidity - disease rate; Motor Skills; National Institute of Child Health and Human Development; Neonatal; Outcome; Population; Population Programs; Population Study; Prevalence; Publishing; Rate; Research; Research Personnel; Resources; Services; Socioeconomic Status; Source; Stress; United States National Institutes of Health; cost; follow-up; handicapping condition; infancy; infant outcome; intervention program; mortality; skills

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Mortality rates have decreased dramatically over the past two decades among extremely low birth weight (ELBW) infants. A large volume of literature focused on outcomes of these infants is available, but a clear definition of the prevalence of handicapping conditions during infancy or childhood has yet to be published. Currently, published studies offer conflicting results and conclusions. Accurate information concerning outcome for ELBW infants is essential when cost versus benefit discussions arise because of the tremendous resources utilized in the care of the ELBW infant. Specifically, study objectives are: - to track and successfully follow at 18 months of age more than 80% of babies entered into the generic database (GDB) of the Neonatal Research Network with birth weights 401-1,500 grams born after January 1, 1993, - to characterize development of the study population by standardized Methods in the areas of motor skills, cognitive skills, language and behavior, - to determine the 18-22 month (corrected age) mortality and the prevalence of specific medical morbidities in extremely low birth weight infants, - to characterize growth outcome and its relationship to neurodevelopmental outcome in this population at 18 months, - to identify the socio-economic status of families in this population and its relationship to developmental outcome, - to identify significant family stress in this population and its relationship to family integrity as well as compliance with medical and developmental care, - to assess the utilization of special support services and early intervention programs by this population. Linking information from the NICHD Neonatal Research Network GDB to a follow-up assessment at 18 months provides a unique opportunity to address health policy debates as well as evaluate the impact of care practices.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 过去二十年来，极低出生体重（ELBW）婴儿的死亡率急剧下降。 有大量关注这些婴儿结局的文献，但婴儿期或儿童期残疾状况的患病率的明确定义尚未发表。 目前，已发表的研究提供了相互矛盾的结果和结论。 由于照顾 ELBW 婴儿需要耗费大量资源，因此在进行成本与效益讨论时，有关 ELBW 婴儿结局的准确信息至关重要。 具体来说，研究目标是： - 跟踪并成功追踪 1993 年 1 月 1 日之后出生的出生体重为 401-1,500 克的 80% 以上的婴儿，这些婴儿在 18 个月大时进入了新生儿研究网络的通用数据库 (GDB)， - 通过标准化方法来描述研究人群在运动技能、认知技能、语言和行为领域的发展， - 确定极低出生体重婴儿的 18-22 个月（校正年龄）死亡率和特定疾病的患病率， - 描述该人群 18 个月时的生长结果及其与神经发育结果的关系， - 确定该人群中家庭的社会经济地位及其与发展成果的关系， - 确定该人群面临的重大家庭压力及其与家庭完整性以及遵守医疗和发育护理的关系， - 评估该人群对特殊支持服务和早期干预计划的利用情况。 将 NICHD 新生儿研究网络 GDB 的信息与 18 个月时的后续评估联系起来，为解决卫生政策辩论以及评估护理实践的影响提供了独特的机会。