MECHANISMS UNDERLYING ENHANCED ALVEOLAR MACROPHAGE ACCESSORY FUNCTION IN HIV

HIV 肺泡巨噬细胞辅助功能增强的机制

• 批准号: 7606365
• 负责人: Homer L Twigg
• 金额: $ 1.43万
• 依托单位: INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-12-01 至 2007-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7606365
• 关键词: Alveolar Macrophages; Cell Communication; Computer Retrieval of Information on Scientific Projects Database; Funding; Grant; Institution; Measures; Mediator of activation protein; Research; Research Personnel; Resources; Rest; Source; United States National Institutes of Health; cytokine; design

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The current study is designed to investigate mechanisms underlying this enhancement looking at factors and direct cell to cell interactions as potential mediators. The ability of resting and activated AM to release certain lymphoproliferative enhancing cytokines will be measured.

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 目前的研究旨在研究这种增强的潜在机制，寻找各种因素，并将细胞间的相互作用作为潜在的介体。静息和激活的AM释放某些促进淋巴增殖的细胞因子的能力将被测量。