MECHANISMS UNDERLYING ENHANCED ALVEOLAR MACROPHAGE ACCESSORY FUNCTION IN HIV

HIV 肺泡巨噬细胞辅助功能增强的机制

• 批准号: 7379043
• 负责人: Homer L Twigg
• 金额: $ 0.44万
• 依托单位: INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-12-01 至 2006-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7379043
• 关键词: MECHANISMS; UNDERLYING; ENHANCED; ALVEOLAR; MACROPHAGE

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The current study is designed to investigate mechanisms underlying this enhancement looking at factors and direct cell to cell interactions as potential mediators. The ability of resting and activated AM to release certain lymphoproliferative enhancing cytokines will be measured.

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。目前的研究旨在研究这种增强的机制，将因子和直接细胞间相互作用作为潜在的介质。将测量静息和活化的AM释放某些淋巴增殖增强细胞因子的能力。