Research Bronchoscopy and Biospecimens Core

研究支气管镜检查和生物样本核心

• 批准号: 10457992
• 负责人: Homer L Twigg
• 金额: $ 20.33万
• 依托单位: INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-08-01 至 2026-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10457992
• 关键词: Address; Area; Asthma; Basic Science; Biopsy; Blood; Blood specimen; Bronchoalveolar Lavage; Bronchoscopy; Cells; Clinical; Clinical Sciences; Clinical Trials; Data Coordinating Center; Databases; Dimethyl Sulfoxide; Disease; Ensure; Environment; Freezing; Future; Genomics; Goals; Human; Imaging Techniques; In Vitro; Indiana; Infrastructure; Institutes; Label; Lead; Link; Liquid substance; Lung; Measurement; Metadata; Nitrogen; Patients; Peripheral Blood Mononuclear Cell; Plasma; Prevention approach; Process; Proteomics; Protocols documentation; RNA; Research; Research Personnel; Research Project Grants; Resources; Sampling; Scientist; Serum; Services; Specimen; Specimen Handling; Study Subject; Time; Time Study; Tissues; Translational Research; Universities; Work; base; biobank; clinically relevant; design; experimental study; feasibility research; human tissue; innovation; insight; interest; novel strategies; preservation; programs; recruit; skills; translational scientist; translational study

PROJECT SUMMARY/ABSTRACT Core B: Bronchoscopy and Biospecimens The goal of this core is four-fold. First, the core is responsible for performing bronchoscopy on study subjects to obtain all the necessary lung specimens for in vitro experiments. This includes collecting all the appropriate control specimens at the time of study. Second, the core is responsible for processing specimens in such a way that they can either be used real time or stored appropriately for future use. This includes coordination of processing and storage protocols between labs. Third, the core is responsible for aliquoting samples in appropriate sizes and conditions (i.e. RNA preservation media, DMSO) for storage in appropriate environments (i.e. -80o freezer, liquid nitrogen) for future studies. Finally, the core is responsible for labeling and tracking all specimens, including the linkage of specimens to subject metadata. By providing uniform specimens to all investigators the core can ensure interdisciplinary integration of the multiple projects that make up the combined Program Project.

项目总结/文摘