METABOLIC RESPONSE TO 4 DIETARY FIBER IN HUMAN SUBJECTS

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 众所周知，膳食纤维会影响胃肠道，尽管不同的膳食纤维在改变胃肠道健康的能力上存在显著差异。这项研究的目的是比较4种膳食纤维在正常人中的生理反应，并与安慰剂治疗进行比较。这项研究的次要目的是测量膳食纤维对血液化学指标的影响，包括血脂、血糖、胰岛素、C反应蛋白和胃肠激素。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Dietary fiber is known to affect the gastrointestinal (GI) tract, although there are significant differences among dietary fiber on their abililty to alter GI health. The objective of this study is to compare the physiological responses of 4 dietary fibers in normal human subjects, as compared to a placebo treatment. Secondary aims of the study are to measure the effects of dietary fibers on blood chemistries, including blood lipids, glucose, insulin, C-reactive protein, and gut hormones.