METABOLIC RESPONSE TO 4 DIETARY FIBER IN HUMAN SUBJECTS

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得主要资金， 因此可以在其他CRISP条目中表示。列出的机构是 研究中心，而研究中心不一定是研究者所在的机构。 众所周知，膳食纤维会影响胃肠道（GI），尽管膳食纤维在改变GI健康的能力方面存在显着差异。本研究的目的是比较正常人受试者中4种膳食纤维与安慰剂治疗的生理反应。这项研究的第二个目的是测量膳食纤维对血液化学的影响，包括血脂、葡萄糖、胰岛素、C反应蛋白和肠道激素。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Dietary fiber is known to affect the gastrointestinal (GI) tract, although there are significant differences among dietary fiber on their abililty to alter GI health. The objective of this study is to compare the physiological responses of 4 dietary fibers in normal human subjects, as compared to a placebo treatment. Secondary aims of the study are to measure the effects of dietary fibers on blood chemistries, including blood lipids, glucose, insulin, C-reactive protein, and gut hormones.