PACTG 1025

PACTG 1025

• 批准号: 7607616
• 负责人: Juan C Salazar
• 金额: $ 0.19万
• 依托单位: UNIVERSITY OF CONNECTICUT SCH OF MED/DNT
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-04-01 至 2008-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7607616
• 关键词: Adherence; Affect; Cohort Studies; Collection; Computer Retrieval of Information on Scientific Projects Database; Data Analyses; Data Collection; Drug Kinetics; Effectiveness of Interventions; Evaluation; Funding; Grant; HIV; Infant; Institution; Patient currently pregnant; Postpartum Period; Postpartum Women; Pregnancy; Pregnant Women; Prevention; Research; Research Personnel; Resources; Risk Factors; Source; Specimen; United States National Institutes of Health; Vertical Disease Transmission; Women' s Health; Work; antiretroviral therapy; concept; infant and toddler safety intervention; infant outcome; prospective; repository

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. PACTG P1025 is a prospective cohort study that provides a framework for collection and evaluation of data and collection of repository specimens from Human Immunodeficiency Virus (HIV)-infected pregnant and postpartum women and their infants. The primary objectives of this study are: to assess the effectiveness of interventions (e.g. antiretroviral therapy and mode of delivery) prescribed for prevention of vertical transmission of HIV and/or for women's health; to assess material and infant safety of interventions (e.g. Antiretroviral Therapy (ART) and mode of delivery) prescribed for women's health and/or for prevention of vertical transmission of HIV; to provide a framework and specimen repository for intensive substudies (such as PACTG P1026s, pharmacokinetics in pregnancy), New Works Concept Sheets (NWCS) and Data Analysis Concept Sheets (DACS) that aim to further elucidate risk factors for and mechanisms of vertical transmission of HIV, as well as factors that affect maternal and infant outcomes; to assess adherence to ART among HIV-infected pregnant women during pregnancy and postpartum and its impact on women's health and vertical transmission, and to assess adherence to chemoprophylaxsis in infants.

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