ORAL CANDIDA
ORAL CANDIDA
批准号:
7607610
负责人:
Anna I Dongari-Bagtzoglou
金额:
$0.98万
依托单位国家:
美国
项目类别:
财政年份:
2007
资助国家:
美国
项目状态:
已结题
起止时间:
2007-04-01 至 2008-03-31
关键词:
Antifungal AgentsCandidaCellsComputer Retrieval of Information on Scientific Projects DatabaseEpithelial CellsFundingGrantImmuneImmunocompromised HostInstitutionNeutrophil ActivationOpportunistic InfectionsOralOral candidiasisProteinsPurposeResearchResearch PersonnelResistanceResourcesSourceTestingUnited States National Institutes of Healthcell typecytokinefungusneutrophilresponse
中文摘要
这个子项目是许多研究子项目中利用
资源由NIH/NCRR资助的中心拨款提供。子项目和
调查员(PI)可能从NIH的另一个来源获得了主要资金,
并因此可以在其他清晰的条目中表示。列出的机构是
该中心不一定是调查人员的机构。
口腔念珠菌病可能是与免疫功能受损的宿主有关的最常见的机会性感染。抵抗念珠菌的最重要的免疫细胞类型是中性粒细胞(PMN)。虽然这些细胞被认为在抵抗和根除真菌方面很重要,但这些功能的表达需要被称为细胞因子的可溶性蛋白质激活。在免疫受损的宿主中,这些分子更有可能来自非免疫来源的细胞,如上皮细胞。本研究的目的是检测口腔上皮细胞分泌的细胞因子对中性粒细胞抗真菌功能的激活作用。
英文摘要
This subproject is one of many research subprojects utilizing the
resources provided by a Center grant funded by NIH/NCRR. The subproject and
investigator (PI) may have received primary funding from another NIH source,
and thus could be represented in other CRISP entries. The institution listed is
for the Center, which is not necessarily the institution for the investigator.
Oral candidiasis is perhaps the most frequent opportunistic infection associated with an immunocompromised host. The most important immune cell type in the defense against Candida is the neutrophil (PMN). Although these cells are considered important in the resistance to and eradication of fungi, expression of these functions requires activation by soluble proteins known as cytokines. In the immunocompromised host these molecules are more likely to be derived from cells of non-immune origin, such as epithelial cells. The purpose of this study is to test the activation of neutrophil anti-fungal functions in response to cytokines secreted by oral epithelial cells.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Control of heterogeneous microbial communities using model-based multi-objective optimization
-
批准号:10268262
-
项目类别:
-
资助金额:$42.18万
-
财政年份:2018
-
负责人:Anna I Dongari-Bagtzoglou
-
依托单位:
Control of heterogeneous microbial communities using model-based multi-objective optimization
-
批准号:10267334
-
项目类别:
-
资助金额:$42.18万
-
财政年份:2018
-
负责人:Anna I Dongari-Bagtzoglou
-
依托单位:
Model of chemotherapy-induced mucositis
-
批准号:8871565
-
项目类别:
-
资助金额:$19.94万
-
财政年份:2014
-
负责人:Anna I Dongari-Bagtzoglou
-
依托单位:
Model of chemotherapy-induced mucositis
-
批准号:8770223
-
项目类别:
-
资助金额:$22.97万
-
财政年份:2014
-
负责人:Anna I Dongari-Bagtzoglou
-
依托单位:
Oral Epithelial Cells, Candida and PMN Activation
-
批准号:7932529
-
项目类别:
-
资助金额:$21.34万
-
财政年份:2009
-
负责人:Anna I Dongari-Bagtzoglou
-
依托单位:
ORAL INFECTION AND INFLAMMATION IN TRANSPLANT PATIENTS
-
批准号:7719123
-
项目类别:
-
资助金额:$0.79万
-
财政年份:2008
-
负责人:Anna I Dongari-Bagtzoglou
-
依托单位:
ORAL CANDIDA
-
批准号:7719112
-
项目类别:
-
资助金额:$0.83万
-
财政年份:2008
-
负责人:Anna I Dongari-Bagtzoglou
-
依托单位:
ORAL INFECTION AND INFLAMMATION IN TRANSPLANT PATIENTS
-
批准号:7607625
-
项目类别:
-
资助金额:$2.83万
-
财政年份:2007
-
负责人:Anna I Dongari-Bagtzoglou
-
依托单位:
ORAL INFECTION AND INFLAMMATION IN TRANSPLANT PATIENTS
-
批准号:7377365
-
项目类别:
-
资助金额:$8.38万
-
财政年份:2006
-
负责人:Anna I Dongari-Bagtzoglou
-
依托单位:
ORAL INFECTION AND INFLAMMATION IN TRANSPLANT PATIENTS
-
批准号:7203965
-
项目类别:
-
资助金额:$0.08万
-
财政年份:2005
-
负责人:Anna I Dongari-Bagtzoglou
-
依托单位:
ORAL CANDIDA
-
批准号:7203940
-
项目类别:
-
资助金额:$0.12万
-
财政年份:2005
-
负责人:Anna I Dongari-Bagtzoglou
-
依托单位:
Oral infection and inflammation in transplant patients
-
批准号:6887257
-
项目类别:
-
资助金额:$21.75万
-
财政年份:2004
-
负责人:Anna I Dongari-Bagtzoglou
-
依托单位:
Oral Candida
-
批准号:6975313
-
项目类别:
-
资助金额:$0.55万
-
财政年份:2004
-
负责人:Anna I Dongari-Bagtzoglou
-
依托单位:
Oral infection and inflammation in transplant patients
-
批准号:6949093
-
项目类别:
-
资助金额:$18.13万
-
财政年份:2004
-
负责人:Anna I Dongari-Bagtzoglou
-
依托单位:
ORAL MUCOSAL CELLS, CANDIDA AND CYTOKINE PRODUCTION
-
批准号:6379848
-
项目类别:
-
资助金额:$4.26万
-
财政年份:2000
-
负责人:Anna I Dongari-Bagtzoglou
-
依托单位:
ORAL EPITHELIAL CELL CYTOKINES CANDIDA & PMN ACTIVATION
-
批准号:6524120
-
项目类别:
-
资助金额:$18.49万
-
财政年份:2000
-
负责人:Anna I Dongari-Bagtzoglou
-
依托单位:
Oral Epithelial Cells, Candida and PMN Activation
-
批准号:10668279
-
项目类别:
-
资助金额:$58.52万
-
财政年份:2000
-
负责人:Anna I Dongari-Bagtzoglou
-
依托单位:
Oral Epithelial Cells, Candida and PMN Activation
-
批准号:10451819
-
项目类别:
-
资助金额:$56.47万
-
财政年份:2000
-
负责人:Anna I Dongari-Bagtzoglou
-
依托单位:
ORAL EPITHELIAL CELL CYTOKINES CANDIDA & PMN ACTIVATION
-
批准号:6380022
-
项目类别:
-
资助金额:$21.74万
-
财政年份:2000
-
负责人:Anna I Dongari-Bagtzoglou
-
依托单位:
Oral Epithelial Cells, Candida and PMN Activation
-
批准号:8697320
-
项目类别:
-
资助金额:$41.23万
-
财政年份:2000
-
负责人:Anna I Dongari-Bagtzoglou
-
依托单位:
国内基金
海外基金
登录
查看更多内容
活性代谢物 OA 调控 Hog1 介导 Candida albicans 死亡
的机制研究
-
批准号:2024JJ6396
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2024
-
负责人:彭雪玲
-
依托单位:
白符䖴(Folsomia candida)的物种分化及其孤雌生殖的调控机制
-
批准号:--
-
项目类别:--
-
资助金额:58万元
-
批准年份:2021
-
负责人:栾云霞
-
依托单位:
白符䖴(Folsomia candida)的物种分化及其孤雌生殖的调控机制
-
批准号:32170425
-
项目类别:面上项目
-
资助金额:58.00万元
-
批准年份:2021
-
负责人:栾云霞
-
依托单位:
Candida glycerinogenes耐受高浓度2-苯乙醇的调控机制
-
批准号:31601456
-
项目类别:青年科学基金项目
-
资助金额:20.0万元
-
批准年份:2016
-
负责人:陆信曜
-
依托单位:
Candida glycerinogenes过量合成甘油过程中渗透压对EMP/HMP途径代谢偏转的调控研究
-
批准号:31270080
-
项目类别:面上项目
-
资助金额:78.0万元
-
批准年份:2012
-
负责人:诸葛斌
-
依托单位:
假丝酵母Candida属的分子分类学研究
-
批准号:39700001
-
项目类别:青年科学基金项目
-
资助金额:13.0万元
-
批准年份:1997
-
负责人:白逢彦
-
依托单位: